Faculty Scholarship
Showing 61 - 70 of 733 Items
Date: 2017-01-01
Creator: A. Luna, S. Melville, S. G. Naculich, C. D. White
Access: Open access
- We examine the Regge (high energy) limit of 4-point scattering in both QCD and gravity, using recently developed techniques to systematically compute all corrections up to next-to-leading power in the exchanged momentum i.e. beyond the eikonal approximation. We consider the situation of two scalar particles of arbitrary mass, thus generalising previous calculations in the literature. In QCD, our calculation describes power-suppressed corrections to the Reggeisation of the gluon. In gravity, we confirm a previous conjecture that next-to-soft corrections correspond to two independent deflection angles for the incoming particles. Our calculations in QCD and gravity are consistent with the well-known double copy relating amplitudes in the two theories.
Date: 2009-07-01
Creator: Anja Forche, P. T. Magee, Anna Selmecki, Judith Berman, Georgiana, May
Access: Open access
- The mechanisms and rates by which genotypic and phenotypic variation is generated in opportunistic, eukaryotic pathogens during growth in hosts are not well understood. We evaluated genomewide genetic and phenotypic evolution in Candida albicans, an opportunistic fungal pathogen of humans, during passage through a mouse host (in vivo) and during propagation in liquid culture (in vitro). We found slower population growth and higher rates of chromosome-level genetic variation in populations passaged in vivo relative to those grown in vitro. Interestingly, the distribution of long-range loss of heterozygosity (LOH) and chromosome rearrangement events across the genome differed for the two growth environments, while rates of short-range LOH were comparable for in vivo and in vitro populations. Further, for the in vivo populations, there was a positive correlation of cells demonstrating genetic alterations and variation in colony growth and morphology. For in vitro populations, no variation in growth phenotypes was detected. Together, our results demonstrate that passage through a living host leads to slower growth and higher rates of genomic and phenotypic variation compared to in vitro populations. Results suggest that the dynamics of population growth and genomewide rearrangement contribute to the maintenance of a commensal and opportunistic life history of C. albicans. Copyright © 2009 by the Genetics Society of America.
Date: 2019-02-05
Creator: W. K. Smith, E. Nelson, J. A. Johnson, S. Polasky, J. C., Milder, J. S. Gerber, P. C. West, S. Siebert, K. A. Brauman
Access: Open access
- Voluntary sustainability standards (VSS) are stakeholder-derived principles with measurable and enforceable criteria to promote sustainable production outcomes. While institutional commitments to use VSS to meet sustainable procurement policies have grown rapidly over the past decade, we still have relatively little understanding of the (i) direct environmental benefits of large-scale VSS adoption; (ii) potential perverse indirect impacts of adoption; and (iii) implementation pathways. Here, we illustrate and address these knowledge gaps using an ecosystem service modeling and scenario analysis of Bonsucro, the leading VSS for sugarcane. We find that global compliance with the Bonsucro environmental standards would reduce current sugarcane production area (−24%), net tonnage (−11%), irrigation water use (−65%), nutrient loading (−34%), and greenhouse gas emissions from cultivation (−51%). Under a scenario of doubled global sugarcane production, Bonsucro adoption would further limit water use and greenhouse gas emissions by preventing sugarcane expansion into water-stressed and high-carbon stock ecosystems. This outcome was achieved via expansion largely on existing agricultural lands. However, displacement of other crops could drive detrimental impacts from indirect land use. We find that over half of the potential direct environmental benefits of Bonsucro standards under the doubling scenario could be achieved by targeting adoption in just 10% of global sugarcane production areas. However, designing policy that generates the most environmentally beneficial Bonsucro adoption pathway requires a better understanding of the economic and social costs of VSS adoption. Finally, we suggest research directions to advance sustainable consumption and production.
Date: 2012-01-01
Creator: William K. Richard, Stephen M. Majercik
Access: Open access
Date: 2019-07-03
Creator: Crystal Hall
Access: Open access
- This article examines the relationship between two fields of study, Italian Studies and Digital Humanities (DH), by documenting projects that employ digital or computational methods in the study of Italian language, literature, history, and the arts. In a complementary fashion, the author outlines the analytical questions of Italian scholars that have potential to advance inquiry in DH. A final section is devoted to contextualizing DH within the practice of Italian Studies at the institutional, program, and department levels by drawing on research of course offerings and a survey circulated in August 2017. The overall finding is that the area of overlap between DH and Italian Studies is intellectually rich, with increasing (yet still sparse) opportunities to develop specialization in this area.
Date: 2010-10-01
Creator: Wayne H. Slade, Emmanuel Boss, Giorgio Dall'olmo, M. Rois Langner, James, Loftin, Michael J. Behrenfeld, Collin Roesler, Toby K. Westberry
Access: Open access
- Optical sensors have distinct advantages when used in ocean observatories, autonomous platforms, and on vessels of opportunity, because of their high-frequency measurements, low power consumption, and the numerous established relationships between optical measurements and biogeochemical variables. However, the issues of biofouling and instrument stability over time remain complicating factors when optical instruments are used over periods longer than several days. Here, a method for obtaining calibration-independent measurements of spectral particle absorption and attenuation is presented. Flow-through optical instrumentation is routinely diverted through a large-surface area 0.2-μm cartridge filter, allowing for the calculation of particle optical properties by differencing temporally adjacent filtered and whole water samples. This approach yields measurements that are independent of drift in instrument calibration. The method has advantages not only for coastally moored deployments, but also for applications in optically clear waters where uncertainties in instrument calibration can be a significant part of the signal measured. The differencing technique is demonstrated using WET Labs (Philomath, Oregon) ac-9 and ac-s multi- and hyperspectral absorption and attenuation meters. For the ac-s sensor, a correction scheme is discussed that utilizes the spectral shape of water absorption in the near-infrared to improve the accuracy of temperature and scattering-corrected spectra. Flow-through particulate absorption measurements are compared with discrete filter-pad measurements and are found to agree well (R = 0.77; rmse = 0.0174 m ). © 2010 American Meteorological Society. 2 -1
Date: 1995-01-01
Creator: Eric Chown, Stephen Kaplan, David Kortenkamp
Access: Open access
- An integrated representation of large-scale space, or cognitive map, colled PLAN, is presented that attempts to address a broader spectrum of issues than has been previously attempted in a single model. Rather than examining way-finding as a process separate from the rest of cognition, one or the fundamental goals of this work is to examine how the wayfinding process is integrated into general cognition. One result of this approach is that the model is "heads-up," or scene-based, because it takes advantage of the properties of the human visual system and, particularly, the visual system's split into two pathways. The emphasis on the human location or "where" system is new to cognitive mapping and is port of an attempt to synthesize prototype theory, associative networks and location together in a connectionist system. Not all of PLAN is new, however. Many of its parts have analogues in one or another preexisting theory. What makes PLAN unique is integrating the various components into a coherent whole, and the capacity of this resulting system to speak to a wide range of constraints. Our approach emphasizes adaptiveness; thus, our focus on such issues as ease of use and efficiency of learning. The result is a model that has a stronger relationship both to the environment, and to the ways that humans interact with it, compared with previous models. The resulting model is examined in some detail and compared to other systems. © 1995.
Date: 2013-03-10
Creator: Yao Tang, Daniel Shapiro, Miaojun Wang, Weiying Zhang
Access: Open access
- We investigate the degree to which corporate governance and ownership affects the innovation performance of firms in China with a particular focus on privately owned small and medium enterprises (SMEs). We hypothesize that (1) board-related governance measures will enhance innovation because they improve monitoring and provide access to necessary resources; (2) ownership concentration initially facilitates innovation because large shareholders are more likely to commit to the long-term nature of innovation, and have the incentive to monitor managers whose time horizon may be shorter; however we argue that these effects weaken as large shareholders becomes entrenched at higher levels of concentration; and (3) hiring an external CEO will enhance innovation both by ensuring professional management of the company, and by alleviating the entrenchment possibilities associated with large shareholders. These hypotheses are tested using a unique sample of 370 mostly private and relatively small Chinese firms in Zhejiang province, for the period 2004 to 2006. The results suggest that for this sample, corporate governance and ownership affect innovation activity when measured by patenting activity, but not when measured by new product sales.
Date: 2014-12-01
Creator: Nathaniel T Wheelwright, Nalini M Nadkarni
Access: Open access
- La Reserva Biológica Bosque Nuboso Monteverde ha capturado la atención mundial de biólogos, conservacionistas y ecólogos y allí se han hecho vastas investigaciones durante los últimos 40 años. Unos 40.000 ecoturistas visitan el Bosque Nuboso cada año y se considera el bosque lluvioso arquetípico de las altitudes altas. Este libro, una traducción actualizada de "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", editado por Nalini Nadkarni y Nathaniel T. Wheelwright (Oxford University Press, 2000) presenta capítulos sintéticos y recuentos específicos escritos por más de 100 biólogos y residentes locales. En un solo volumen documenta todo lo que se sabe en 2014 de la diversidad biológica de Monteverde, Costa Rica, y cómo protegerla. The Monteverde Cloud Forest Reserve has captured the worldwide attention of biologists, conservationists, and ecologists and has been the setting for extensive investigation over the past 40 years. Roughly 40,000 ecotourists visit the Cloud Forest each year, and it is often considered the archetypal high-altitude rain forest. This book, an updated and expanded version of "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", edited by Nalini Nadkarni and Nathaniel T. Wheelwright (Oxford University Press, 2000), features synthetic chapters and specific accounts written by more than 100 biologists and local residents. The 862-page book includes 12 new short chapters and documents in a single volume everything known in 2014 about the biological diversity of Monteverde, Costa Rica, and how to protect it. El texto del libro ha sido dividido en dos partes para leer en línea: Parte 1: Agradecimientos, Prólogos, Capítulos 1-7 Parte 2: Capítulos 8-12, Appéndices Para hacer zoom, haga clic en la página. Para encontrar en el libro referencias a cualquier tema, especie, etc., haga clic en el “Q,” espere hasta la pantalla nueva, haga clic en el “Q” otra vez, y entre la palabra clave.
Date: 2010-01-01
Creator: Elizabeth A. Stemmler, Emily A. Bruns, Christopher R. Cashman, Patsy S. Dickinson, Andrew E., Christie
Access: Open access
- The PISCF-allatostatins (Manduca sexta- or C-type allatostatins) are a family of pentadecapeptides characterized by a pyroglutamine blocked N-terminus, an unamidated-PISCF C-terminus, and a disulfide bridge between two internal Cys residues. Several isoforms of PISCF-AST are known, all from holometabolous insects. Using a combination of transcriptomics and mass spectrometry, we have identified the first PISCF-type peptides from a non-insect species. In silico analysis of crustacean ESTs identified several Litopenaeus vannamei (infraorder Penaeidea) transcripts encoding putative PISCF-AST precursors. Translation of these ESTs, with subsequent prediction of their putative post-translational processing, revealed the existence of as many as three PISCF-type peptides, including pQIRYHQCYFNPISCF (disulfide bridging between Cys7 and Cys14). Although none of the predicted isoforms was detected by mass spectrometry in L. vannamei, MALDI-FTMS mass profiling identified an m/z signal corresponding to pQIRYHQCYFNPISCF (disulfide bridge present) in neural tissue from 28 other decapods, which included members of six infraorders (Stenopodidea, Astacidea, Thalassinidea, Achelata, Anomura and Brachyura). Further characterization of the peptide using SORI-CID and chemical derivatization/enzymatic digestion supported the theorized structure. In both the crab Cancer borealis and the lobster Homarus americanus, MALDI-based tissue surveys suggest that pQIRYHQCYFNPISCF is broadly distributed in the nervous system; it was also detected in the posterior midgut caecum. Collectively, our data show that members of the PISCF-AST family are not restricted to the holometabolous insects, but instead may be broadly conserved within the Pancrustacea. Moreover, our data suggest that one highly conserved PISCF-type peptide, pQIRYHQCYFN-PISCF, is present in decapod crustaceans, functioning as a brain-gut paracrine/hormone. © 2009 Elsevier Inc. All rights reserved.