Simplified insertion of transgenes onto balancer chromosomes via recombinase-mediated cassette exchange

Date: 2012-05-01

Creator: Florence F. Sun, Justine E. Johnson, Martin P. Zeidler, Jack R. Bateman

Access: Open access

Balancer chromosomes are critical tools for Drosophila genetics. Many useful transgenes are inserted onto balancers using a random and inefficient process. Here we describe balancer chromosomes that can be directly targeted with transgenes of interest via recombinase-mediated cassette exchange (RMCE). ©2012 Sun et al.