Honors Projects

Showing 511 - 520 of 662 Items

The Role of ELMO5 in Arabidopsis thaliana Cell Adhesion

Date: 2022-01-01

Creator: Isabel Kristina Ball

Access: Open access

Plant cell growth and development relies on proper cellular adhesion. As the extracellular matrix serves as the area of connection between two cells, its synthesis and maintenance are essential for cellular adhesion. The middle lamella region, the layer of the extracellular matrix between two adjacent cell walls, is diffuse with the polysaccharide pectin due to its delivery by Golgi vesicles early during cell division. A Ruthenium Red screen for cellular adhesion mutants identified the family of 5 ELMO proteins that are critical for proper cellular adhesion. To further our understanding of plant cellular adhesion and pathways of pectin synthesis and modification, this work investigates ELMO5. Plants homozygous for a T-DNA insertion in ELMO5 and a new deletion mutant allele generated using CRSPR do not have a cellular adhesion phenotype, suggesting it is either not critical for cellular adhesion or is redundant with another gene. Redundancy within the ELMO family is identified through the analysis of double mutants of elmo5 and each of the other four elmo genes. Both elmo1-/- elmo5-/-and elmo4-/- elmo5-/-mutants have a visibly worse cellular adhesion defect phenotype, suggesting partial redundancy through the ELMO family. The mutants are also rescued by growth on agar, pointing to the importance of turgor pressure and osmotic potential in modulating cellular adhesion. Both ELMO4 and ELMO5 were found to localize to the Golgi using a GFP fusion, consistent with a role for ELMOs as scaffold for pectin biosynthesis.


Miniature of Characterization of Spaetzle-Toll Ligand-Receptor Pairs in <i>Gryllus bimaculatus</i>
Characterization of Spaetzle-Toll Ligand-Receptor Pairs in Gryllus bimaculatus
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  • Restriction End Date: 2028-06-01

    Date: 2023-01-01

    Creator: Tabarak Al Musawi

    Access: Access restricted to the Bowdoin Community



      Miniature of Literary <i>Stolpersteine</i> that Produce Memory, Identity, and Belonging in Contemporary German Narratives of Migration
      Literary Stolpersteine that Produce Memory, Identity, and Belonging in Contemporary German Narratives of Migration
      This record is embargoed.
        • Embargo End Date: 2026-12-16

        Date: 2022-01-01

        Creator: Lauren Katz

        Access: Embargoed



          Miniature of Ink
          Ink
          This record is embargoed.
            • Embargo End Date: 2025-05-19

            Date: 2022-01-01

            Creator: Andrew MacGregor Nicholson

            Access: Embargoed



              Miniature of An analysis and characterization of Sonic Hedgehog and Fgf genes in <i>Danio rerio</i> embryonic tooth development
              An analysis and characterization of Sonic Hedgehog and Fgf genes in Danio rerio embryonic tooth development
              This record is embargoed.
                • Embargo End Date: 2027-05-18

                Date: 2022-01-01

                Creator: Lauren Kanoelani Waters

                Access: Embargoed



                  Miniature of The influence of Toll 7 on the neuroplasticity of auditory neurons in the Mediterranean field cricket (<i>Gryllus bimaculatus</i>)
                  The influence of Toll 7 on the neuroplasticity of auditory neurons in the Mediterranean field cricket (Gryllus bimaculatus)
                  This record is embargoed.
                    • Embargo End Date: 2028-05-16

                    Date: 2023-01-01

                    Creator: Brooke Asherman

                    Access: Embargoed



                      Miniature of From Shadow to Spotlight:  Minoritarian Characters, Representative Failures,  and High School Powerarchy in Teen Television
                      From Shadow to Spotlight: Minoritarian Characters, Representative Failures, and High School Powerarchy in Teen Television
                      This record is embargoed.
                        • Embargo End Date: 2028-05-18

                        Date: 2023-01-01

                        Creator: Paloma Ada Aguirre

                        Access: Embargoed



                          Miniature of <i>Onkel Toms Hütte</i>: Translation, Intervention, and Nation
                          Onkel Toms Hütte: Translation, Intervention, and Nation
                          This record is embargoed.
                            • Embargo End Date: 2028-05-18

                            Date: 2023-01-01

                            Creator: Sofie Brown

                            Access: Embargoed



                              Miniature of The Roles of Personality, Internalized Stigma, and Shame Proneness as Barriers to Mental Health Treatment
                              The Roles of Personality, Internalized Stigma, and Shame Proneness as Barriers to Mental Health Treatment
                              Access to this record is restricted to members of the Bowdoin community. Log in here to view.
                              • Restriction End Date: 2026-06-01

                                Date: 2023-01-01

                                Creator: Grace Cross

                                Access: Access restricted to the Bowdoin Community



                                  Miniature of Examining the Predictive Value of Anxiety, Depression, and Suicidal Ideation Screening in Determining Psychosis Risk
                                  Examining the Predictive Value of Anxiety, Depression, and Suicidal Ideation Screening in Determining Psychosis Risk
                                  This record is embargoed.
                                    • Embargo End Date: 2028-05-16

                                    Date: 2023-01-01

                                    Creator: Tara M. D. Mullen

                                    Access: Embargoed