Honors Projects
Showing 511 - 520 of 662 Items
The Role of ELMO5 in Arabidopsis thaliana Cell Adhesion
Date: 2022-01-01
Creator: Isabel Kristina Ball
Access: Open access
- Plant cell growth and development relies on proper cellular adhesion. As the extracellular matrix serves as the area of connection between two cells, its synthesis and maintenance are essential for cellular adhesion. The middle lamella region, the layer of the extracellular matrix between two adjacent cell walls, is diffuse with the polysaccharide pectin due to its delivery by Golgi vesicles early during cell division. A Ruthenium Red screen for cellular adhesion mutants identified the family of 5 ELMO proteins that are critical for proper cellular adhesion. To further our understanding of plant cellular adhesion and pathways of pectin synthesis and modification, this work investigates ELMO5. Plants homozygous for a T-DNA insertion in ELMO5 and a new deletion mutant allele generated using CRSPR do not have a cellular adhesion phenotype, suggesting it is either not critical for cellular adhesion or is redundant with another gene. Redundancy within the ELMO family is identified through the analysis of double mutants of elmo5 and each of the other four elmo genes. Both elmo1-/- elmo5-/-and elmo4-/- elmo5-/-mutants have a visibly worse cellular adhesion defect phenotype, suggesting partial redundancy through the ELMO family. The mutants are also rescued by growth on agar, pointing to the importance of turgor pressure and osmotic potential in modulating cellular adhesion. Both ELMO4 and ELMO5 were found to localize to the Golgi using a GFP fusion, consistent with a role for ELMOs as scaffold for pectin biosynthesis.

Characterization of Spaetzle-Toll Ligand-Receptor Pairs in Gryllus bimaculatus Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2028-06-01
Date: 2023-01-01
Creator: Tabarak Al Musawi
Access: Access restricted to the Bowdoin Community

Literary Stolpersteine that Produce Memory, Identity, and Belonging in Contemporary German Narratives of Migration This record is embargoed.
- Embargo End Date: 2026-12-16
Date: 2022-01-01
Creator: Lauren Katz
Access: Embargoed

Ink This record is embargoed.
- Embargo End Date: 2025-05-19
Date: 2022-01-01
Creator: Andrew MacGregor Nicholson
Access: Embargoed

An analysis and characterization of Sonic Hedgehog and Fgf genes in Danio rerio embryonic tooth development This record is embargoed.
- Embargo End Date: 2027-05-18
Date: 2022-01-01
Creator: Lauren Kanoelani Waters
Access: Embargoed

The influence of Toll 7 on the neuroplasticity of auditory neurons in the Mediterranean field cricket (Gryllus bimaculatus) This record is embargoed.
- Embargo End Date: 2028-05-16
Date: 2023-01-01
Creator: Brooke Asherman
Access: Embargoed

From Shadow to Spotlight: Minoritarian Characters, Representative Failures, and High School Powerarchy in Teen Television This record is embargoed.
- Embargo End Date: 2028-05-18
Date: 2023-01-01
Creator: Paloma Ada Aguirre
Access: Embargoed

Onkel Toms Hütte: Translation, Intervention, and Nation This record is embargoed.
- Embargo End Date: 2028-05-18
Date: 2023-01-01
Creator: Sofie Brown
Access: Embargoed

The Roles of Personality, Internalized Stigma, and Shame Proneness as Barriers to Mental Health Treatment Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2026-06-01
Date: 2023-01-01
Creator: Grace Cross
Access: Access restricted to the Bowdoin Community

Examining the Predictive Value of Anxiety, Depression, and Suicidal Ideation Screening in Determining Psychosis Risk This record is embargoed.
- Embargo End Date: 2028-05-16
Date: 2023-01-01
Creator: Tara M. D. Mullen
Access: Embargoed