Showing 5201 - 5250 of 5840 Items
Date: 2020-01-01
Creator: Rohini Kurup
Access: Open access
- In the wake of the September 11 attacks, the Bush administration decided that suspected terrorists and those determined to have aided terrorists would be detained and classified as “enemy combatants.” This was a largely new category of prisoners who were neither prisoners of war protected under international law nor civilians. They included noncitizens and citizens—those captured on foreign battlefields and on American soil. They would be detained by the United States, held indefinitely without charge or access to a lawyer, and subject to trial by military commission. The administration’s enemy combatant policies were based on a theory of inherent executive power—that the Constitution gave the president vast and exclusive powers, which allowed him to act unilaterally without Congressional interference or judicial review. This thesis charts the development of and challenges to the enemy combatant policies to understand how they were conceived and what their implications are to the American political system. I argue that by appealing to a theory of inherent executive power to create the policies, the administration subverted traditional checks on presidential power and undermined the rule of law. Ultimately, the dismantling of some of the enemy combatant policies, largely a result of court rulings that challenged the administration’s premise of power, signified a reining in of executive authority. Yet, many aspects of the administration’s counterterrorism apparatus remained past Bush’s years in the White House, leaving a legacy of expanded presidential power for future presidents.

Date: 2020-01-01
Creator: Frances DeCamp Hobart Zorensky
Access: Access restricted to the Bowdoin Community
Date: 2020-01-01
Creator: Jacob Salman Kazmi
Access: Open access
- Neuromodulation may be a substrate for the evolution of behavioral diversity. The extent to which a central pattern generator is modulated could serve as a mechanism that enables variability in motor output dependent on an organism’s need for behavioral flexibility. The pyloric circuit, a central pattern generator in the crustacean stomatogastric nervous system (STNS), stimulates contractions of foregut muscles in digestion. Since neuromodulation enables variation in the movements of pyloric muscles, more diverse feeding patterns should be correlated with a higher degree of STNS neuromodulation. Previous data have shown that Cancer borealis, an opportunistic feeder, is sensitive to a wider array of neuromodulators than Pugettia producta, a specialist feeder. The observed difference in modulatory capacity may be coincidental since these species are separated by phylogeny. We predict that the difference in modulatory capacity is a product of a differential need for variety in foregut muscle movements. This study examined two members of the same superfamily as P. producta, the opportunistically feeding snow crab (Chionoecetes opilio) and portly spider crab (Libinia emarginata). Using extracellular recording methods, the responses of isolated STNS preparations to various neuromodulators were measured. Initial qualitative results indicate that the STNS of C. opilio is sensitive to all of these neuromodulators. Additionally, previous data on the neuromodulatory capacity of L. emarginata was supported through similar electrophysiological analysis of the isolated STNS. As a first step in determining the mechanism of differential sensitivity between species, tissue-specific transcriptomes were generated and mined for neuromodulators.

Date: 2020-01-01
Creator: Owen Templeton Tuck
Access: Access restricted to the Bowdoin Community
Date: 1911-01-01
Access: Open access
- Bowdoin College Bulletin no. 32
Date: 1980-08-25
Creator: Peter M.M. Rae, Bruce D. Kohorn, Robert P. Wade
Access: Open access
- Most repeat units of rDNA in Drosophila virilis are interrupted in the 28S rRNA coding region by an intervening sequence about 10 kb in length; uninterrupted repeats have a length of about 11 kb. We have sequenced the coding/intervening sequence junctions and flanking regions in two independent clones of interrupted rDNA, and the corresponding 28S rRNA coding region in a clone of uninterrupted rDNA. The intervening sequence is terminated at both ends by a direct repeat of a fourteen nucleotide sequence that is present once in the corresponding region of an intact gene. This is a phenomenon associated with transposable elements in other eukaryotes and in prokaryotes, and the Drosophila rDNA intervening sequence is discussed in this context. We have compared more than 200 nucleotides of the D. virilis 28S rRNA gene with sequences of homologous regions of rDNA in Tetrahymena pigmentosa (Wild and Sommer, 1980) and Xenopus laevis (Gourse and Gerbi, 1980): There is 93% sequence homology among the diverse species, so that the rDNA region in question (about two-thirds of the way into the 28S rRNA coding sequence) has been very highly conserved in eukaryote evolution. The intervening sequence in T. pigmentosa is at a site 79 nucleotides upstream from the insertion site of the Drosophila intervening sequence. © 1980 IRL Press Limited.
Date: 2001-08-24
Creator: Shaun Snyders, Bruce D. Kohorn
Access: Open access
- To survive fluctuations in quality and intensity of light, plants and algae are able to preferentially direct the absorption of light energy to either one of the two photosystems PSI or PSII. This rapid process is referred to as a state transition and has been correlated with the phosphorylation and migration of the light-harvesting complex protein (LHCP) between PSII and PSI. We show here that thylakoid protein kinases (TAKs) are required for state transitions in Arabidopsis. Antisense TAK1 expression leads to a loss of LHCP phosphorylation and a reduction in state transitions. Preferential activation of PSII causes LHCP to accumulate with PSI, and TAK1 mutants disrupt this process. Finally, TAKs also influence the phosphorylation of multiple thylakoid proteins.
Date: 2014-01-01
Creator: Andrea Rosen
Access: Open access
- "Accompanies an exhibition of the same name at the Bowdoin College Museum of Art, February 27 through June 1, 2014." Foreword by Frank H. Goodyear III; essay: Conceal and reveal : layering techniques in surrealist photography by Andrea Rosen.
Date: 2013-10-23
Creator: Patricia L. Jones, Michael J. Ryan, Victoria Flores, Rachel A. Page
Access: Open access
- Animals can use different sources of information when making decisions. Foraging animals often have access to both self-acquired and socially acquired information about prey. The fringe-lipped bat, Trachops cirrhosus, hunts frogs by approaching the calls that frogs produce to attract mates.We examined howthe reliability of self-acquired prey cues affects social learning of novel prey cues. We trained bats to associate an artificial acoustic cue (mobile phone ringtone) with food rewards. Bats were assigned to treatments in which the trained cue was either an unreliable indicator of reward (rewarded 50% of the presentations) or a reliable indicator (rewarded 100% of the presentations), and they were exposed to a conspecific tutor foraging on a reliable (rewarded 100%) novel cue or to the novel cue with no tutor. Bats whose trained cue was unreliable and who had a tutor were significantly more likely to preferentially approach the novel cue when compared with bats whose trained cue was reliable, and to bats that had no tutor. Reliability of self-acquired prey cues therefore affects social learning of novel prey cues by frog-eating bats. Examining when animals use social information to learn about novel prey is key to understanding the social transmission of foraging innovations. © 2013 The Author(s) Published by the Royal Society.
Date: 1914-01-01
Access: Open access
- Bowdoin College Bulletin no. 49
Date: 2020-01-01
Creator: Ian Ward
Access: Open access
- Hans-Georg Gadamer’s myriad contributions to the continental philosophical tradition have been well documented, but his influence on North American intellectual life has gone largely gone unrecognized. This paper attempts to fill that gap, using primary and secondary source material to document Gadamer’s scholarly activities in the United States and Canada between 1968 and 1986. The paper also evaluates Gadamer’s influence using detailed accounts of “hermeneutic encounters” that occurred between Gadamer and four notable North American philosophers: Richard Palmer, Paul de Man, Charles Taylor, and Richard Rorty. Through these accounts, this paper argues that Gadamer made lasting contributions to ongoing debates in the humanities about the nature of literary interpretation, the social sciences, and analytic philosophy. Finally, the paper explores the philosophical and historiological possibilities that Gadamer’s hermeneutics opens up for intellectual history more broadly, especially in the field of reception history. Building on Gadamer’s own hermeneutics and Hans-Robert Jauss’s reception aesthetics, it develops the concept of the “encounter” as the starting point of a more hermeneutically-sensitive approach to intellectual history.
Date: 2009-07-28
Creator: Ruth Griffin, Anne Sustar, Marianne Bonvin, Richard Binari, Alberto, del Valle Rodriguez, Amber M. Hohl, Jack R. Bateman, Christians Villalta, Elleard Heffern, Didier Grunwald, Chris Bakal, Claude Desplan, Gerold Schubiger, C. Ting Wu, Norbert Perrimon
Access: Open access
- In Drosophila melanogaster, widely used mitotic recombination-based strategies generate mosaic flies with positive readout for only one daughter cell after division. To differentially label both daughter cells, we developed the twin spot generator (TSG) technique, which through mitotic recombination generates green and red twin spots that are detectable after the first cell division as single cells. We propose wide applications of TSG to lineage and genetic mosaic studies.
Date: 1999-01-01
Creator: Zachary Wills, Jack Bateman, Christopher A. Korey, Allen Comer, David, Van Vactor
Access: Open access
- Genetic analysis of growth cone guidance choice points in Drosophila identified neuronal receptor protein tyrosine phosphatases (RPTPs) as key determinants of axon pathfinding behavior. We now demonstrate that the Drosophila Abl tyrosine kinase functions in the intersegmental nerve b (ISNb) motor choice point pathway as an antagonist of the RPTP Dlar. The function of Abl in this pathway is dependent on an intact catalytic domain. We also show that the Abl phosphoprotein substrate Enabled (Ena) is required for choice point navigation. Both Abl and Ena proteins associate with the Dlar cytoplasmic domain and serve as substrates for Dlar in vitro, suggesting that they play a direct role in the Dlar pathway. These data suggest that Dlar, Abl, and Ena define a phosphorylation state-dependent switch that controls growth cone behavior by transmitting signals at the cell surface to the actin cytoskeleton.
Date: 1925-01-01
Access: Open access
- Bowdoin College Bulletin no. 137
Date: 1918-01-01
Access: Open access
- Bowdoin College Bulletin no. 68
Date: 1921-01-01
Access: Open access
- Bowdoin College Bulletin no. 104
Date: 1920-01-01
Access: Open access
- Bowdoin College Bulletin no. 95
Date: 2021-04-01
Creator: Julian R. Garrison, Joshua S. Caplan, Vladimir Douhovnikoff, Thomas J. Mozdzer, Barry A. Logan
Access: Open access
- PREMISE: Biological invasions increasingly threaten native biodiversity and ecosystem services. One notable example is the common reed, Phragmites australis, which aggressively invades North American salt marshes. Elevated atmospheric CO2 and nitrogen pollution enhance its growth and facilitate invasion because P. australis responds more strongly to these enrichments than do native species. We investigated how modifications to stomatal features contribute to strong photosynthetic responses to CO2 and nitrogen enrichment in P. australis by evaluating stomatal shifts under experimental conditions and relating them to maximal stomatal conductance (gwmax) and photosynthetic rates. METHODS: Plants were grown in situ in open-top chambers under ambient and elevated atmospheric CO2 (eCO2) and porewater nitrogen (Nenr) in a Chesapeake Bay tidal marsh. We measured light-saturated carbon assimilation rates (Asat) and stomatal characteristics, from which we calculated gwmax and determined whether CO2 and Nenr altered the relationship between gwmax and Asat. RESULTS: eCO2 and Nenr enhanced both gwmax and Asat, but to differing degrees; gwmax was more strongly influenced by Nenr through increases in stomatal density while Asat was more strongly stimulated by eCO2. There was a positive relationship between gwmax and Asat that was not modified by eCO2 or Nenr, individually or in combination. CONCLUSIONS: Changes in stomatal features co-occur with previously described responses of P. australis to eCO2 and Nenr. Complementary responses of stomatal length and density to these global change factors may facilitate greater stomatal conductance and carbon gain, contributing to the invasiveness of the introduced lineage.
Date: 1938-01-01
Access: Open access
- Bowdoin College Bulletin no. 240
Date: 2020-01-01
Creator: Siena Brook Ballance
Access: Open access
- Phytoplankton underpin marine trophic systems and biogeochemical cycles. Estuarine and coastal phytoplankton account for 40-50% of global ocean primary productivity and carbon flux making it critical to identify sources of variability. This project focuses on the Kennebec River and Harpswell Sound, a downstream, but hydrologically connected coastal estuary, as a case study of temperate river influence on estuarine nutrient regimes and phytoplankton communities. Phytoplankton pigments and nutrients were analyzed from water samples collected monthly at 8 main-stem rivers stations (2011-2013) and weekly in Harpswell Sound (2008-2017) during ice-free months. Spatial bedrock and land use impacts on river nutrients were investigated at sub-watershed scales using GIS. Spatial analysis reveals a 10-fold increase in measured phytoplankton biomass across the Kennebec River’s saltwater boundary, which demonstrates ocean-driven phytoplankton variability in the lower river. The biomass pattern is accompanied by a transition in phytoplankton community structure with respect to which groups co-occur (diatoms, chlorophytes, and cryptophytes) and which are unique (dinoflagellates in Harpswell). Upstream, the timing of each community depends on land-use proximity and seasonal discharge. In Harpswell Sound, the nutrient regime and phytoplankton community structure vary systematically: first diatoms strip silicate, then dinoflagellates utilize nitrate, followed by chlorophytes and cryptophytes that utilize available phosphate. These findings reveal, for the first time, patterns in phytoplankton communities and nutrient dynamics across the fresh to salt water interface. Ultimately the Kennebec River phytoplankton communities and nutrient regimes are distinct, and the river is only a source of silicate to Harpswell Sound.

Date: 2020-01-01
Creator: Luca Ostertag-Hill
Access: Access restricted to the Bowdoin Community
Date: 1944-01-01
Access: Open access
- Bowdoin College Bulletin no. 269
Date: 1936-01-01
Access: Open access
- Bowdoin College Bulletin no. 228
Date: 1945-01-01
Access: Open access
- Bowdoin College Bulletin no. 273
Date: 2020-01-01
Creator: Diego Rafael Grossmann
Access: Open access
- The Colombo-Venezuelan Border Through the Lens of the Colombian Press examines the dominant Colombian press coverage of crises of sovereignty at the Colombo-Venezuelan border, Venezuelan migration, and the February 2019 attempt to introduce humanitarian aid into Venezuela, as seen in El Espectador and El Tiempo’s coverage from the period of August 2018-November 2019. Through theories of nations and power, this thesis reveals the divergent editorial lines and dominant narratives within each newspaper’s construction of the relation between the Colombian and Venezuelan nations, states, and their people. The study details how both newspapers construct different “truths” through divergent constructions of similar events in a manner coherent with the ideological affinities and conceptions of Colombian national identity held by their respective audiences and editorial leadership, constrained further by economic factors. The thesis is split into three main chapters. Chapter 1 addresses the construction of Colombian nationhood rooted in militarism and the presentation of the Colombian state as a protector in El Tiempo’s coverage concerning binational tensions at the border. Chapter 2 traces the coverage regarding Venezuelan migration to Colombia within El Espectador, detailing the conception of national identity rooted in liberal-democratic values that the newspaper constructs and appeals to. Chapter 3 considers both newspaper’s coverage of the attempt to introduce humanitarian aid into Venezuela in 2019. Ultimately, this thesis argues that the discursive actor––and construction––of Venezuela permits the “imagining” of the Colombian nation, a project framed through a discussion of the Colombian conflict and official commitments to multiculturalism by the Colombian state.
Date: 1948-01-01
Access: Open access
- Bowdoin College Bulletin no. 287
Date: 1950-01-01
Access: Open access
- Bowdoin College Bulletin no. 295
Date: 2018-07-01
Creator: Andrew E. Christie, Andy Yu, Micah G. Pascual, Vittoria Roncalli, Matthew C., Cieslak, Amanda N. Warner, Tess J. Lameyer, Meredith E. Stanhope, Patsy S. Dickinson, J. Joe Hull
Access: Open access
- Essentially all organisms exhibit recurring patterns of physiology/behavior that oscillate with a period of ~24-h and are synchronized to the solar day. Crustaceans are no exception, with robust circadian rhythms having been documented in many members of this arthropod subphylum. However, little is known about the molecular underpinnings of their circadian rhythmicity. Moreover, the location of the crustacean central clock has not been firmly established, although both the brain and eyestalk ganglia have been hypothesized as loci. The American lobster, Homarus americanus, is known to exhibit multiple circadian rhythms, and immunodetection data suggest that its central clock is located within the eyestalk ganglia rather than in the brain. Here, brain- and eyestalk ganglia-specific transcriptomes were generated and used to assess the presence/absence of transcripts encoding the commonly recognized protein components of arthropod circadian signaling systems in these two regions of the lobster central nervous system. Transcripts encoding putative homologs of the core clock proteins clock, cryptochrome 2, cycle, period and timeless were found in both the brain and eyestalk ganglia assemblies, as were transcripts encoding similar complements of putative clock-associated, clock input pathway and clock output pathway proteins. The presence and identity of transcripts encoding core clock proteins in both regions were confirmed using PCR. These findings suggest that both the brain and eyestalk ganglia possess all of the molecular components needed for the establishment of a circadian signaling system. Whether the brain and eyestalk clocks are independent of one another or represent a single timekeeping system remains to be determined. Interestingly, while most of the proteins deduced from the identified transcripts are shared by both the brain and eyestalk ganglia, assembly-specific isoforms were also identified, e.g., several period variants, suggesting the possibility of region-specific variation in clock function, especially if the brain and eyestalk clocks represent independent oscillators.

Date: 2021-01-01
Creator: Eugen Florin Cotei
Access: Access restricted to the Bowdoin Community
Date: 2009-04-15
Creator: Patsy S. Dickinson, Teerawat Wiwatpanit, Emily R. Gabranski, Rachel J. Ackerman, Jake S., Stevens, Christopher R. Cashman, Elizabeth A. Stemmler, Andrew E. Christie
Access: Open access
- The allatostatins comprise three structurally distinct peptide families that regulate juvenile hormone production by the insect corpora allata. A-type family members contain the C-terminal motif -YXFGLamide and have been found in species from numerous arthropod taxa. Members of the B-type family exhibit a -WX6Wamide C-terminus and, like the A-type peptides, appear to be broadly conserved within the Arthropoda. By contrast, members of the C-type family, typified by the unblocked C-terminus -PISCF, a pyroglutamine blocked N-terminus, and a disulfide bridge between two internal Cys residues, have only been found in holometabolous insects, i.e. lepidopterans and dipterans. Here, using transcriptomics, we have identified SYWKQCAFNAVSCFamide (disulfide bridging predicted between the two Cys residues), a known honeybee and water flea C-typelike peptide, from the American lobster Homarus americanus (infraorder Astacidea). Using matrix assisted laser desorption/ionization Fourier transform mass spectrometry (MALDI-FTMS), a mass corresponding to that of SYWKQCAFNAVSCFamide was detected in the H. americanus brain, supporting the existence of this peptide and its theorized structure. Furthermore, SYWKQCAFNAVSCFamide was detected by MALDI-FTMS in neural tissues from five additional astacideans as well as 19 members of four other decapod infraorders (i.e. Achelata, Anomura, Brachyura and Thalassinidea), suggesting that it is a broadly conserved decapod peptide. In H. americanus, SYWKQCAFNAVSCFamide is capable of modulating the output of both the pyloric circuit of the stomatogastric nervous system and the heart. This is the first demonstration of bioactivity for this peptide in any species.
Date: 2018-07-01
Creator: Harrison P. Fisher, Micah G. Pascual, Sylvia I. Jimenez, David A. Michaelson, Colby T., Joncas, Eleanor D. Quenzer, Andrew E. Christie, Hadley W. Horch
Access: Open access
- The auditory system of the cricket, Gryllus bimaculatus, demonstrates an unusual amount of anatomical plasticity in response to injury, even in adults. Unilateral removal of the ear causes deafferented auditory neurons in the prothoracic ganglion to sprout dendrites across the midline, a boundary they typically respect, and become synaptically connected to the auditory afferents of the contralateral ear. The molecular basis of this sprouting and novel synaptogenesis in the adult is not understood. We hypothesize that well-conserved developmental guidance cues may recapitulate their guidance functions in the adult in order to facilitate this compensatory growth. As a first step in testing this hypothesis, we have generated a de novo assembly of a prothoracic ganglion transcriptome derived from control and deafferented adult individuals. We have mined this transcriptome for orthologues of guidance molecules from four well-conserved signaling families: Slit, Netrin, Ephrin, and Semaphorin. Here we report that transcripts encoding putative orthologues of most of the candidate developmental ligands and receptors from these signaling families were present in the assembly, indicating expression in the adult G. bimaculatus prothoracic ganglion.
Date: 2019-08-01
Creator: Samantha K. Barry, Taro Nakamura, Yuji Matsuoka, Christoph Straub, Hadley W., Horch, Cassandra G. Extavour
Access: Open access
- Altering gene function in a developing organism is central to different kinds of experiments. While tremendously powerful genetic tools have been developed in traditional model systems, it is difficult to manipulate genes or messenger RNA (mRNA) in most other organisms. At the same time, evolutionary and comparative approaches rely on an exploration of gene function in many different species, necessitating the development and adaptation of techniques for manipulating expression outside currently genetically tractable species. This protocol describes a method for injecting reagents into cricket eggs to assay the effects of a given manipulation on embryonic or larval development. Instructions for how to collect and inject eggs with beveled needles are described. This relatively straightforward technique is flexible and potentially adaptable to other insects. One can gather and inject dozens of eggs in a single experiment, and survival rates for buffer-only injections improve with practice and can be as high as 80%. This technique will support several types of experimental approaches including injection of pharmacological agents, in vitro capped mRNA to express genes of interest, double-stranded RNA (dsRNA) to achieve RNA interference, use of clustered regularly interspaced short palindromic repeats (CRISPR) in concert with CRISPR-associated protein 9 (Cas9) reagents for genomic modification, and transposable elements to generate transient or stable transgenic lines.

Date: 2021-01-01
Creator: Melissa G. Demczak
Access: Access restricted to the Bowdoin Community

Date: 2021-01-01
Creator: Ben Cook
Access: Access restricted to the Bowdoin Community

Date: 2015-05-01
Creator: Stephanie Lane
Access: Access restricted to the Bowdoin Community

Date: 2021-01-01
Creator: Alex Baselga Garriga
Access: Access restricted to the Bowdoin Community