Showing 201 - 210 of 5709 Items
Interview with Patrick Hunt by Mike Hastings
Date: 2008-09-27
Creator: Patrick E Hunt
Access: Open access
Biographial Note
Patrick E. Hunt was born on August 19, 1946, in Bangor, Maine, and grew up in Island Falls with his parents, Theodore E. Hunt and Margaret I. Doherty, and his three sisters. Theodore attended Husson College, and operated a restaurant in Island Falls until the 1960s, when he became the village postmaster; Margaret was from Boston, a graduate of Charlestown High School, and of Irish descent from Clonmany County, Donegal. Patrick attended Ricker College, entered the Army in 1968, and served in Korea; he completed his degree in economics at Ricker in 1971. Subsequently, he joined the Drug Enforcement Administration of the United States Department of Justice in Massachusetts, attending evening law school courses, before returning to Island Falls in 1983 to start his own law practice. He was still practicing there at the time of this interview.
Summary
Interview includes discussion of: family and educational background; Island Falls, Maine, community; Ed Muskie’s ideas for economic improvements; Drug Enforcement Administration; George Mitchell as U.S. attorney; politic aspects of U.S. Attorney’s Office; family background and Joe Doherty’s Northern Ireland story; George Mitchell’s work in Northern Ireland; thoughts on George Mitchell as president; and politics and economics in Aroostook County.
Monteverde: ecología y conservación de un bosque nuboso tropical
Date: 2014-12-01
Creator: Nathaniel T Wheelwright, Nalini M Nadkarni
Access: Open access
- La Reserva Biológica Bosque Nuboso Monteverde ha capturado la atención mundial de biólogos, conservacionistas y ecólogos y allí se han hecho vastas investigaciones durante los últimos 40 años. Unos 40.000 ecoturistas visitan el Bosque Nuboso cada año y se considera el bosque lluvioso arquetípico de las altitudes altas. Este libro, una traducción actualizada de "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", editado por Nalini Nadkarni y Nathaniel T. Wheelwright (Oxford University Press, 2000) presenta capítulos sintéticos y recuentos específicos escritos por más de 100 biólogos y residentes locales. En un solo volumen documenta todo lo que se sabe en 2014 de la diversidad biológica de Monteverde, Costa Rica, y cómo protegerla. The Monteverde Cloud Forest Reserve has captured the worldwide attention of biologists, conservationists, and ecologists and has been the setting for extensive investigation over the past 40 years. Roughly 40,000 ecotourists visit the Cloud Forest each year, and it is often considered the archetypal high-altitude rain forest. This book, an updated and expanded version of "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", edited by Nalini Nadkarni and Nathaniel T. Wheelwright (Oxford University Press, 2000), features synthetic chapters and specific accounts written by more than 100 biologists and local residents. The 862-page book includes 12 new short chapters and documents in a single volume everything known in 2014 about the biological diversity of Monteverde, Costa Rica, and how to protect it. El texto del libro ha sido dividido en dos partes para leer en línea: Parte 1: Agradecimientos, Prólogos, Capítulos 1-7 Parte 2: Capítulos 8-12, Appéndices Para hacer zoom, haga clic en la página. Para encontrar en el libro referencias a cualquier tema, especie, etc., haga clic en el “Q,” espere hasta la pantalla nueva, haga clic en el “Q” otra vez, y entre la palabra clave.
Experiments in Gender: A Comparative Analysis on the Literary Representation of Women in Medicine and Science during the Weimar Republic Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2021-01-01
Creator: Rachel Bercovitch
Access: Access restricted to the Bowdoin Community
The History of Bowdoin College: With Biographical Sketches of Its Graduates from 1806 to 1879, Inclusive
Date: 1882-01-01
Creator: Nehemiah Cleaveland, Alpheus S. Packard
Access: Open access
- The History of Bowdoin College: With Biographical Sketches of Its Graduates from 1806 to 1879, Inclusive (1882), by Nehemiah Cleaveland and Alpheus S. Packard, provides encyclopedic biographical sketches of Bowdoin presidents and graduates for most of the nineteenth century, along with engraved portraits for many of them.
Modulation of ionic currents by nitric oxide negative feedback in the lobster cardiac ganglion Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2026-06-01
Date: 2021-01-01
Creator: Emily Renee King
Access: Access restricted to the Bowdoin Community
Molecular and mass spectral identification of the broadly conserved decapod crustacean neuropeptide pQIRYHQCYFNPISCF: The first PISCF-allatostatin (Manduca sexta- or C-type allatostatin) from a non-insect
Date: 2010-01-01
Creator: Elizabeth A. Stemmler, Emily A. Bruns, Christopher R. Cashman, Patsy S. Dickinson, Andrew E., Christie
Access: Open access
- The PISCF-allatostatins (Manduca sexta- or C-type allatostatins) are a family of pentadecapeptides characterized by a pyroglutamine blocked N-terminus, an unamidated-PISCF C-terminus, and a disulfide bridge between two internal Cys residues. Several isoforms of PISCF-AST are known, all from holometabolous insects. Using a combination of transcriptomics and mass spectrometry, we have identified the first PISCF-type peptides from a non-insect species. In silico analysis of crustacean ESTs identified several Litopenaeus vannamei (infraorder Penaeidea) transcripts encoding putative PISCF-AST precursors. Translation of these ESTs, with subsequent prediction of their putative post-translational processing, revealed the existence of as many as three PISCF-type peptides, including pQIRYHQCYFNPISCF (disulfide bridging between Cys7 and Cys14). Although none of the predicted isoforms was detected by mass spectrometry in L. vannamei, MALDI-FTMS mass profiling identified an m/z signal corresponding to pQIRYHQCYFNPISCF (disulfide bridge present) in neural tissue from 28 other decapods, which included members of six infraorders (Stenopodidea, Astacidea, Thalassinidea, Achelata, Anomura and Brachyura). Further characterization of the peptide using SORI-CID and chemical derivatization/enzymatic digestion supported the theorized structure. In both the crab Cancer borealis and the lobster Homarus americanus, MALDI-based tissue surveys suggest that pQIRYHQCYFNPISCF is broadly distributed in the nervous system; it was also detected in the posterior midgut caecum. Collectively, our data show that members of the PISCF-AST family are not restricted to the holometabolous insects, but instead may be broadly conserved within the Pancrustacea. Moreover, our data suggest that one highly conserved PISCF-type peptide, pQIRYHQCYFN-PISCF, is present in decapod crustaceans, functioning as a brain-gut paracrine/hormone. © 2009 Elsevier Inc. All rights reserved.
To what extent may peptide receptor gene diversity/complement contribute to functional flexibility in a simple pattern-generating neural network?
Date: 2019-06-01
Creator: Patsy S. Dickinson, J. Joe Hull, Alexandra Miller, Emily R. Oleisky, Andrew E., Christie
Access: Open access
- Peptides are known to contribute to central pattern generator (CPG) flexibility throughout the animal kingdom. However, the role played by receptor diversity/complement in determining this functional flexibility is not clear. The stomatogastric ganglion (STG) of the crab, Cancer borealis, contains CPGs that are models for investigating peptidergic control of rhythmic behavior. Although many Cancer peptides have been identified, their peptide receptors are largely unknown. Thus, the extent to which receptor diversity/complement contributes to modulatory flexibility in this system remains unresolved. Here, a Cancer mixed nervous system transcriptome was used to determine the peptide receptor complement for the crab nervous system as a whole. Receptors for 27 peptide families, including multiple receptors for some groups, were identified. To increase confidence in the predicted sequences, receptors for allatostatin-A, allatostatin-B, and allatostatin-C were cloned, sequenced, and expressed in an insect cell line; as expected, all three receptors trafficked to the cell membrane. RT-PCR was used to determine whether each receptor was expressed in the Cancer STG. Transcripts for 36 of the 46 identified receptors were amplified; these included at least one for each peptide family except RYamide. Finally, two peptides untested on the crab STG were assessed for their influence on its motor outputs. Myosuppressin, for which STG receptors were identified, exhibited clear modulatory effects on the motor patterns of the ganglion, while a native RYamide, for which no STG receptors were found, elicited no consistent modulatory effects. These data support receptor diversity/complement as a major contributor to the functional flexibility of CPGs.