Showing 2141 - 2150 of 5831 Items

Miniature of Fluorescent Sugar Analogs as Probes for Bacterial Monosaccharide Uptake
Fluorescent Sugar Analogs as Probes for Bacterial Monosaccharide Uptake
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      Date: 2024-01-01

      Creator: Foje-Geh Robert Tendoh

      Access: Access restricted to the Bowdoin Community




        Miniature of Clam shells and sea temperature: Evaluation of the oxygen isotopic climate proxy in <i>Arctica islandica</i> and development of a shell-derived sea temperature reconstruction from Isle au Haut, Maine
        Clam shells and sea temperature: Evaluation of the oxygen isotopic climate proxy in Arctica islandica and development of a shell-derived sea temperature reconstruction from Isle au Haut, Maine
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            Date: 2024-01-01

            Creator: Brielle Martin

            Access: Access restricted to the Bowdoin Community



              Africa and the International Criminal Court: Behind the Backlash and Toward Future Solutions

              Date: 2017-05-01

              Creator: Marisa O'Toole

              Access: Open access

              Fifteen years into its operation as the preeminent international institution charged with the prosecution of the most serious international crimes, the International Criminal Court (ICC) has faced and continues to face intense backlash from the African continent. Once the Court’s most fervent advocates, many African leaders now lambast the ICC. In recent months, three African countries and the African Union en masse have attempted withdrawal from the Court, thus pushing the ICC-Africa relationship into the international spotlight as a topic of acute global interest. This paper seeks to explore the critiques behind this backlash through both a historical and present-day lens, as well as from the perspectives of African leaders, victims-locals, and civil society actors. In doing so, it investigates historical critiques of the ICTY and ICTR, concerns raised during the Rome Statute negotiations, current African leader perspectives as viewed through the case studies of Darfur, Kenya, Uganda, and the AU-ICC relationship, and present African victim-local and civil society opinions of the Court. By understanding the current and multi-faceted African opposition to the ICC and such criticisms’ historical roots, as well as the pockets of hope for the Court within Africa, this analysis reveals the ICC’s main challenges in its relationship with the African continent. With such hurdles unveiled, the ICC can pursue several strategies, located primarily on the state and individual levels, in its endeavor to address these important critiques and regain African support.


              Using atmospheric O2 and CO2 measurements to determine the stoichiometry of photosynthesis and respiration in a temperate forest

              Date: 2018-01-01

              Creator: Margaret Marie Conley

              Access: Open access

              The O2:CO2 exchange ratio of the terrestrial biosphere (αb) is an important parameter in carbon sink calculations, but its value is not well constrained. We investigate the stoichiometry of O2 and CO2 at Harvard Forest in Petersham, Massachusetts over a span of six years, considering the covariation of O2 and CO2 in forest air during 6-hour periods to determine an average value for the O2:CO2 exchange ratio. This approach provides a way to determine the value of αb averaged across seasonal cycles and species assemblages. Our analysis produces an overall average exchange ratio of -1.06 ± 0.01. Comparing measurements within and above the canopy and during nighttime and daytime periods, we observe that atmospheric dynamics and canopy effects produce lower exchange ratios indicative of an enhanced forest signal at the low intake and for daytime periods. We also see an increase in the exchange ratio in the winter compared to the summer that may reflect changes in plant physiological processes or contamination by a fossil fuel signal. To determine whether our observed ratio is truly representative of αb, we use a simple model to estimate the range of variability in CO2 and O2 mixing ratios expected from local influence alone and use this as a criterion to isolate periods dominated by local exchange, yielding an average summer forest exchange ratio of -1.00 ± 0.02. Our analysis provides insight into the average value and variability of αb for temperate forests for use in calculation of the land carbon sink.



              Modulation of the crustacean cardiac neuromuscular system by the SLY neuropeptide family

              Date: 2024-01-01

              Creator: Grant Griesman

              Access: Open access

              Central pattern generators (CPGs) are neuronal networks that produce rhythmic motor output in the absence of sensory stimuli. Invertebrate CPGs are valuable models of neural circuit dynamics and neuromodulation because they continue to generate fictive activity in vitro. For example, the cardiac ganglion (CG) of the Jonah crab (Cancer borealis) and American lobster (Homarus americanus) contains nine electrochemically coupled neurons that fire bursts of action potentials to trigger a heartbeat. The CG is modulated by neuropeptides, amines, small molecule transmitters, gases, and mechanosensory feedback pathways that enable flexibility and constrain output. One such modulator, the SLY neuropeptide family, was previously shown to be expressed in hormonal release sites and within the CG itself and has unusual processing features. However, its physiological effect was unknown. Here, I performed dose-response experiments in the crab and lobster whole heart and isolated CG to determine the threshold concentration of SLY neuropeptides to which these systems respond. The crab isoform had strong, excitatory effects in the crab whole heart and weakly modulated the crab CG. The lobster isoform weakly modulated the lobster whole heart and CG. Surprisingly, the crab isoform exerted large, variable effects on the lobster system, which suggests that SLY neuropeptides, their receptors, and their signaling pathways may be evolutionarily conserved across these two species. This research contributes to our understanding of how neural circuits can generate flexible output in response to modulation. It may also offer insight into processes influenced by peptidergic neurotransmission in the nervous systems of other animals, including mammals.


              Miniature of Group-theory constraints on color-ordered four-point amplitudes in SO(<i>N</i>) gauge-theories
              Group-theory constraints on color-ordered four-point amplitudes in SO(N) gauge-theories
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                  Date: 2024-01-01

                  Creator: Athis Osathapan

                  Access: Access restricted to the Bowdoin Community




                    Round Table Interview with Mike Hastings, Anita Jensen, Estelle Lavoie, and Mary McAleney by Andrea L’Hommedieu

                    Date: 2008-07-21

                    Creator: Michael 'Mike' M Hastings, Anita Jensen, Estelle Lavoie, Mary E McAleney

                    Access: Open access

                    Biographial Note

                    Michael M. Hastings, a native of Morrill, Maine, graduated from Tilton School (NH) in 1968 and Bowdoin College in 1972. Following a year of graduate study in Public & International Affairs at George Washington University, he worked for seven years as a foreign and defense policy aide to Senator William S. Cohen (1973-1980) and for four years for Senator George J. Mitchell (1980-1984). In October, 1984, he joined the international staff of Catholic Relief Services (CRS) and moved to Africa. Over a span of eight years, he worked as a CRS development administrator in Kenya, Tanzania, Togo and The Gambia. During the same period, he assisted in the provision of emergency food for people displaced by civil wars in the Southern Sudan and Liberia. In 1992, he returned to Maine to direct a “center for excellence,” focusing on aquaculture and economic development. Since 2004, he has worked for the University of Maine as its Director of Research and Sponsored Programs. Between 1992 and 2008, he also served on several civic boards and institutions including the Maine Fishermen’s Forum, The Maine Oil Spill Advisory Committee (which he chaired), the Maine Indian Tribal State Commission, the Down East Institute, and the Maine Sea Grant Policy Advisory Committee. Between 1996 and 2001 he was elected three times to be a member of the Town Council of Hampden, ME, where he resides with his wife, a middle school teacher. Anita Holst-Jensen was born in Karl-Marx-Stadt (Chemnitz), East Germany, on March 16, 1945, to Rasma Rasmanis and Arvids Lusis. Her mother emigrated from Latvia in September of 1944, and Jensen was born in a displaced persons camp, where she lived until she was four years old. Her family eventually emigrated to Australia in 1949, settling in Victoria. Jensen received all of her schooling in Australia and went to university in Melbourne. She married Henning Holst-Jensen, and in 1966 they moved to Perth. When immigration into the United States became possible in 1968, they relocated to the Washington, D.C. area, and Jensen took a job with Investors Overseas Services, later Equity Funding. In 1970, she went to work in Senator Ed Muskie’s office, where she continued until he became secretary of state. She transitioned to George Mitchell’s staff when he was appointed to Muskie’s vacated Senate seat and remained for his fourteen years of Senate service, becoming increasingly involved with speech writing and research. Estelle Lavoie was born in Lewiston, Maine, on November 23, 1949, and grew up there, the youngest of three children. Her father worked as a building contractor until his death in 1964, after which her mother worked part-time as a bank teller. She attended Lewiston public schools and was graduated from Bates College (class of 1971), spending her junior year studying in Switzerland. At the end of 1972, she went to work for Governor Ken Curtis. By September of 1973, she had been hired as part of Senator Ed Muskie’s staff, working first as a caseworker and eventually as his legislative assistant. She attended law school at American University from 1978 to 1981 and transitioned to Senator Mitchell’s staff when he assumed Muskie’s Senate seat. She left Mitchell’s staff in the fall of 1983 and joined the law firm of Preti, Flaherty, Beliveau & Pachios the following June. Her practice has evolved from health law to other political practice issues. She served on the Democratic State Committee from 1986 to 1990 and was a delegate to the 1988 National Convention. Mary Elizabeth McAleney was born on March 18, 1945, in Tuscaloosa, Alabama. Her mother, Helen Irene (Twombly) McAleney, was a Works Progress Administration worker, and her father, William McAleney, was a U.S. Customs officer. Mary came from a strongly Democratic Maine family and was politically active from a young age. She was sent from her home near Vanceboro, Maine, to St. Joseph’s boarding school in South Portland, and from there she went to Merrimac College. After her graduation, she taught high school in Maine, first at St. Joseph’s and then at Catherine McAuley High School. After eight years of teaching, she went into political work. She quickly rose through the ranks during Senator Muskie’s ‘76 campaign and worked for state Senator Jim Tierney. She served in George Mitchell’s U.S. Senate office for ten years (1984-1994), focusing on Maine issues.

                    Summary

                    Interview includes discussion of: how Mary McAleney became Mitchell’s scheduler; the transition from Muskie to Mitchell; how Mitchell’s briefcase would be searched entering the office because initially no one knew who he was; the Elizabeth Taylor story; the cow joke; the 1982 U.S. Senate campaign; anecdotes about when Mitchell accidentally sat in a canoe backwards and when David Emery’s float sank in the Kennebec River; the relationship between Cohen and Mitchell; Mitchell’s gaining the support of one of Estelle Lavoie’s friends because he knew the name spelling; Mitchell’s work ethic; Mitchell’s complimenting Byrd on his history of the Senate; Mitchell eye glasses and the striped belt; visiting Talmadge Plantation after Mitchell’s reelection in 1988; Mitchell’s ability to learn and adapt; Anita Jensen’s experience driving Mitchell to work; Mitchell’s lifestyle in D.C.; Sally Mitchell’s decision to stay in Maine and not become involved in politics; the women’s restroom situation in the Capitol; the machine-gun ban and how Feinstein did not want to come to the Senate floor the day after it passed; Mitchell’s process for examining different points of view; an anecdote about Mitchell’s changing his mind and explaining it to the press; Jensen’s lively discussions with Mitchell; the Rehnquist nomination; the role of the staff in Mitchell’s office; Gayle Cory and her influence in the office and with Mitchell; Buzz Fitzgerald; the dynamics of the Mitchell Senate office and the office organization’s lack of hierarchy; the longevity of the staff; Anita Jensen’s role as the speechwriter; writing updates about China; Larry Benoit’s and David Lemoine’s traveling around Maine to update the voter lists; Larry Benoit; Mitchell’s making sure that there were Mainers working for him; the interns; and the Mitchell Institute.