Showing 2381 - 2390 of 5714 Items
A nuclear narrative: Robert Oppenheimer, autobiography, and public authority
Date: 2010-12-01
Creator: David K. Hecht
Access: Open access
The (Far) Backstory of the U.S.-Colombia Free Trade Agreement
Date: 2013-10-10
Creator: Stephen Meardon
Access: Open access
- In two pairs of episodes, first in 1824 and 1846 and then in 1892 and 1935, similar U.S.-Colombia trade agreements or their enabling laws were embraced first by protectionists and then by free traders. The history of the episodes supports the view that although political institutions exist to curb de facto political power, such power may be wielded to undo the institutions’ intended effects. The doctrinal affinities and interests of political actors are more decisive determinants of the free-trade or protectionist orientation of trade agreements than the agreements’ texts or legal superstructures. The long delay from signing to passage of the current U.S.-Colombia Free Trade Agreement is another case in point.
Four Seasons in Maine: Lois Dodd's Small Plein-Air Paintings
Date: 2004-01-01
Creator: Alison Ferris
Access: Open access
- "Accompanies an exhibition of the same name at the Bowdoin College Museum of Art, Brunswick, Maine, from June 22 through September 5, 2004"--P. 9
Oakeshott, Berlin, and liberalism
Date: 2003-01-01
Creator: Paul Franco
Access: Open access
- This article compares the political philosophies of Michael Oakeshott and Isaiah Berlin, probably the two most important political philosophers in postwar Britain, who, strangely, had very little to do with one another during their illustrious careers. The article focuses on their respective critiques of rationalism and theories of liberal pluralism, arguing that Oakeshott provides the more consistent and philosophically satisfying account in both instances.
Andrea Sulzer: After Nature
Date: 2008-01-01
Creator: Katy Kline
Access: Open access
- " ... accompanies an exhibition of the same name at the Bowdoin College Museum of Art from June 17 through August 27, 2008"--P. 16 Essay by Katy Kline.
Preparing for and managing change: Climate adaptation for biodiversity and ecosystems
Date: 2013-11-01
Creator: Bruce A. Stein, Amanda Staudt, Molly S. Cross, Natalie S. Dubois, Carolyn, Enquist, Roger Griffis, Lara J. Hansen, Jessica J. Hellmann, Joshua J. Lawler
Access: Open access
- The emerging field of climate-change adaptation has experienced a dramatic increase in attention as the impacts of climate change on biodiversity and ecosystems have become more evident. Preparing for and addressing these changes are now prominent themes in conservation and natural resource policy and practice. Adaptation increasingly is viewed as a way of managing change, rather than just maintaining existing conditions. There is also increasing recognition of the need not only to adjust management strategies in light of climate shifts, but to reassess and, as needed, modify underlying conservation goals. Major advances in the development of climate-adaptation principles, strategies, and planning processes have occurred over the past few years, although implementation of adaptation plans continues to lag. With ecosystems expected to undergo continuing climate-mediated changes for years to come, adaptation can best be thought of as an ongoing process, rather than as a fixed endpoint. © The Ecological Society of America.
Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling
Date: 2010-09-01
Creator: Yann Gibert, Laure Bernard, Melanie Debiais-Thibaud, Franck Bourrat, Jean Stephane, Joly, Karen Pottin, Axel Meyer, Sylvie Retaux, David W. Stock, William R. Jackman, Pawat Seritrakul, Gerrit Begemann, Vincent Laudet
Access: Open access
- One of the goals of evolutionary developmental biology is to link specific adaptations to changes in developmental pathways. The dentition of cypriniform fishes, which in contrast to many other teleost fish species possess pharyngeal teeth but lack oral teeth, provides a suitable model to study the development of feeding adaptations. Here, we have examined the involvement of retinoic acid (RA) in tooth development and show that RA is specifically required to induce the pharyngeal tooth developmental program in zebrafish. Perturbation of RA signaling at this stage abolished tooth induction without affecting the development of tooth-associated ceratobranchial bones. We show that this inductive event is dependent on RA synthesis from aldh1a2 in the ventral posterior pharynx. Fibroblast growth factor (FGF) signaling has been shown to be critical for tooth induction in zebrafish, and its loss has been associated with oral tooth loss in cypriniform fishes. Pharmacological treatments targeting the RA and FGF pathways revealed that both pathways act independently during tooth induction. In contrast, we find that in Mexican tetra and medaka, species that also possess oral teeth, both oral and pharyngeal teeth are induced independently of RA. Our analyses suggest an evolutionary scenario in which the gene network controlling tooth development obtained RA dependency in the lineage leading to the cypriniforms. The loss of pharyngeal teeth in this group was cancelled out through a shift in aldh1a2 expression, while oral teeth might have been lost ultimately due to deficient RA signaling in the oral cavity. © FASEB.