Showing 2841 - 2850 of 5831 Items
Physiological responses of the American lobster cardiovascular system to neuropeptide SGRNFLRFamide (SGRN)
Date: 2024-01-01
Creator: Andre Eden
Access: Open access
- During every second of a human’s life, the cardiovascular system is modulated by factors both intrinsic and extrinsic to the physiology of the heart. We can uncover new insights regarding the nature of our system through investigations of similar systems in other model species. One example materializes itself in the form of the American Lobster (Homarus americanus) whose single-chambered heart finds resemblance to the function and anatomy to that of humans. The lobster heart is powered by the cardiac ganglion (CG), a group of neurons that drive contractions of surrounding heart muscles, known as the myocardium. Both the CG and myocardium work in a feedback loop, with both intrinsic (afterload and preload) and extrinsic (temperature and neuropeptides) factors affecting cardiac output (CO) or the overall ability of the heart to carry out its primary function of nutrient distribution. In this paper, we examine how the addition of these factors into in vitro whole heart preparations affect CO and other associated variables. From experimentation, we conclude that the neuropeptide SGRNFLRFamide (SGRN) increases the heartbeat frequency and the active force exerted by the heart. We also conclude that increases in temperature decrease CO as higher temperatures decrease heartbeat frequency and the active force exerted by the heart. Lastly, we conclude that the effect of preload and afterload combined produce more robust effects on the CO and active force of the heart, potentially painting a better picture of what may happen in vivo.
Giving on the Margin: The Power of Donor Recognition
Date: 2016-05-01
Creator: Jordan W Richmond
Access: Open access
- This study develops a controlled laboratory experiment to examine the effects of personal recognition on charitable giving. I find evidence that both the possibility of acquiring prestige and the desire to avoid shame motivate individuals to give in recognition situations. Furthermore, I show that the possibility of being recognized is more important than the distinguishing value of that recognition, suggesting that an offer of recognition has greater power to increase charitable contributions when a larger proportion of donors will be recognized.
Interview with Noah Gavil (Class of 2014), Marta Misiulaityte (Class of 2014), and Shannon Grimes (Class of 2014) by Meagan Doyle
Date: 2019-05-31
Creator: Noah Gavil, Marta Misiulaityte, Shannon Grimes
Access: Open access
- Noah Gavil (Class of 2014), Marta Misiulaityte (Class of 2014), and Shannon Grimes (Class of 2014) reflect together on the way their different paths led to Bowdoin and to friendship with one another. They speak about the trials and triumphs of trying to find one’s place as well as the difficulty of learning to manage the pressures and expectations that they felt as Bowdoin students. Additionally, they comment in depth on their study-away experiences and describe the passions and interests their abroad experiences sparked in them. The three touch on a wide range of extracurricular activities, on-campus jobs, and areas of study, and reminisce fondly on the relationships they built with peers, faculty, and staff.
The EOL Enhancer Activates Eya Expression to Mediate Visual System Development in Drosophila melanogaster This record is embargoed.
- Embargo End Date: 2027-05-16
Date: 2024-01-01
Creator: Benjamin Sewell-Grossman
Access: Embargoed
"This people which I made": The Character of King Arthur as a Mechanism of Unification in Medieval Arthuriana and the Idylls of the King
Date: 2016-05-01
Creator: Hallie Schaeffer
Access: Open access
Reframing Mourning: Liberatory Grief in Post-Tragedy Chinese American Women’s Fiction
Date: 2024-01-01
Creator: Sophia Li
Access: Open access
- My project approaches discussions of Asian American melancholia and mourning with a specific focus on contemporary Chinese American women’s fiction. Scholars such as David Eng, Shinhee Han, and Anne Anlin Cheng have long spotlighted the prevalence of depression among Asian American populations, particularly those with immigrant backgrounds, and they variously adopt psychoanalytic approaches to understand Asian American mental health and intersectional identities. Looking beyond psychoanalytic models, my project focuses on the works of Yiyun Li, Jenny Zhang, and K-Ming Chang to explore diverse forms of post-tragedy positionality. I read the authors paratextually, not only to locate them within legacies of diasporic fiction and intersectional auto-writing but also to highlight their critically self-reflexive authorship. I study novels and characters depicting complex processes of mourning, ultimately proposing a reading that views them not only as resisting complete recovery but as forging pathways toward liberatory grief.
Damned If You Do, Damned If You Don't: A Logical Analysis of Moral Dilemmas
Date: 2018-05-01
Creator: Samuel Monkman
Access: Open access
- This project explores the logical structure of moral dilemmas. I introduce the notion of genuine contingent moral dilemmas, as well as basic topics in deontic logic. I then examine two formal arguments claiming that dilemmas are logically impossible. Each argument relies on certain principles of normative reasoning sometimes accepted as axioms of deontic logic. I argue that the principle of agglomeration and a statement of entailment of obligations are both not basic to ethical reasoning, concluding that dilemmas will be admissible under some logically consistent ethical theories. In the final chapter, I examine some consequences of admitting dilemmas into a theory, in particular how doing so complicates assignment of blame.
Characterizing the Motor Activity Patterns of the Mammalian Thoracic Spinal Cord Neural Network This record is embargoed.
- Embargo End Date: 2027-05-16
Date: 2024-01-01
Creator: Sam McClelland
Access: Embargoed
A histological investigation of Arceuthobium pusillum infections in Picea rubens and Picea glauca
Date: 2024-01-01
Creator: Sade K. McClean
Access: Open access
- Arceuthobium pusillum is a hemiparasite that infects select Picea species. The hosts of A. pusillum do not experience the same symptoms of infection. A. pusillum infections are more fatal to P. marinara, and P. glauca. P. rubens, on the other hand, can survive longer with sustained infection. This presents itself as a contemporary issue because P. glauca, one of the parasite’s most vulnerable hosts, was untethered from ecological competition when old growth forests were subjected to large scale anthropogenic disturbances. These disturbances allowed P. glauca to proliferate, with A. pusillum following. A deeper understanding of the host-species specific responses to A. pusillum infection can broaden general knowledge of parasitic growth and development while also potentially inspiring conservation techniques. This study took advantage of the intrinsic differences between host and parasite to visualize infections in P. rubens and P. glauca, highlighting differences in infection outcome. By illuminating lignin and callose within cross sections of infected P. rubens and P. glauca branches, it was revealed that P. rubens forms dense bands of cells around the cortical strands of infection. These bands form more frequently in P. rubens than in P. glauca and are of a significantly larger area in P. rubens than in P. glauca (t(8), p=0.003, p=0.005). The discovery of the exterior bands is novel and exciting, as the bands are possibly made of callose and potentially facilitate P. rubens survival against A. pusillum infection. The foundational discoveries and results of this study should inspire, and warrant, further analysis.
Are People Blaming Artificial Intelligence More or Less for Incorrect Advice? Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2029-06-01
Date: 2024-01-01
Creator: Anh Nguyen
Access: Access restricted to the Bowdoin Community