Showing 3371 - 3380 of 5831 Items
The Architecture of Bowdoin College
Date: 1988-01-01
Creator: Patricia McGraw Anderson
Access: Open access
- The Architecture of Bowdoin College (1988), by Patricia McGraw Anderson, is the best single resource for the architectural history of Bowdoin’s campus buildings, gates, and memorials.
Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila
Date: 2021-06-01
Creator: Myron Child, Jack R. Bateman, Amir Jahangiri, Armando Reimer, Nicholas C., Lammers, Nica Sabouni, Diego Villamarin, Grace C. McKenzie-Smith, Justine E. Johnson, Daniel Jost, Hernan G. Garcia
Access: Open access
- 3D eukaryotic genome organization provides the structural basis for gene regulation. In Drosophila melanogaster, genome folding is characterized by somatic homolog pairing, where homologous chromosomes are intimately paired from end to end; however, how homologs identify one another and pair has remained mysterious. Recently, this process has been proposed to be driven by specifically interacting “buttons” encoded along chromosomes. Here, we turned this hypothesis into a quantitative biophysical model to demonstrate that a button-based mechanism can lead to chromosome-wide pairing. We tested our model using live-imaging measurements of chromosomal loci tagged with the MS2 and PP7 nascent RNA labeling systems. We show solid agreement between model predictions and experiments in the pairing dynamics of individual homologous loci. Our results strongly support a button-based mechanism of somatic homolog pairing in Drosophila and provide a theoretical framework for revealing the molecular identity and regulation of buttons.
Catalogue of the Marbles, Gems, Bronzes, and Coins of the Warren Collection of Greek and Roman Antiquities
Date: 1934-01-01
Access: Open access
- Descriptive catalogue of the Warren Classical Collection of Bowdoin College.
Robert Birmelin: Recent Paintings, Maine and New York
Date: 1980-01-01
Access: Open access
- Catalogue of an exhibition held at Bowdoin College Museum of Art, Mar. 14 to May 25, 1980.