Showing 3511 - 3520 of 5713 Items

Miniature of A multifaceted analysis of Semaphorin-induced neuroplasticity in the nervous system of <i>Gryllus bimaculatus</i>
A multifaceted analysis of Semaphorin-induced neuroplasticity in the nervous system of Gryllus bimaculatus
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  • Restriction End Date: 2028-06-01

    Date: 2023-01-01

    Creator: Ean Lev Small

    Access: Access restricted to the Bowdoin Community



      Invisible Ailments: A Collection

      Date: 2023-01-01

      Creator: Jane L. Godiner

      Access: Open access

      "Invisible Ailments" is a collection of short stories that trace the depth, breath, and sweeping range of lived experiences of people struggling with mental illness. While it is a work of fiction, the people in these stories might feel eerily familiar — to your friends, your family members, your loved ones, or, if you're brave enough to admit it, yourself.


      Miniature of Live imaging of somatic homolog pairing in <i>Drosophila</i> supports a button-based mechanism for pairing facilitated by the genetic insulator <i>gypsy</i>
      Live imaging of somatic homolog pairing in Drosophila supports a button-based mechanism for pairing facilitated by the genetic insulator gypsy
      This record is embargoed.
        • Embargo End Date: 2026-05-18

        Date: 2023-01-01

        Creator: Holden D. Hadfield

        Access: Embargoed



          Miniature of The Impact of Toll 6-1 Function on the Maintenance and Plasticity of the <i>Gryllus bimaculatus</i> Auditory System
          The Impact of Toll 6-1 Function on the Maintenance and Plasticity of the Gryllus bimaculatus Auditory System
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          • Restriction End Date: 2028-06-01

            Date: 2023-01-01

            Creator: Jada Scotland

            Access: Access restricted to the Bowdoin Community



              Characterizing the Roles of Toll7 in the Gryllus Bimaculatus Peripheral Nervous System Development

              Date: 2023-01-01

              Creator: Rowland Luo

              Access: Open access

              The study of neuronal development could provide foundational information on neurogenesis and neuroplasticity. The small size and relatively simple nervous system of Orthoptera make them ideal models for neurodevelopmental studies. The peripheral nervous system development is an intricate and precise process that each sensory neurons are able to reach their central nervous system partners in a relatively short amount of time. Although the peripheral nervous system in limb buds and their genetic regulations are well understood in grasshopper embryos, few studies have explored the developing nervous system in a cricket model. Therefore, the first goal of the current experiment is to characterize the normal peripheral nervous system development in cricket embryos. Previous studies in Drosophila have suggested Toll6 and Toll7 receptors could serve as important targets for the neurotrophic-like factors Spaetzle2 and 5. Malfunctioning neurotrophic pathways could lead to abnormal nervous system development. Therefore, the second goal of the current study is to explore the roles of Toll7 in the development of the cricket peripheral nervous system. Immunohistochemical staining using anti-horseradish peroxidase (Anti-HRP) was used to illustrate crickets' embryonic developing peripheral nervous system in the limb buds from developmental stage 7.0 to 11.0. Cricket eggs were injected with Toll7 double stranded RNA (dsRNA) and rhodamine dye to suppress the Toll7 mRNA level. The control eggs were injected with GFP dsRNA and rhodamine dye. The peripheral nervous system development in cricket embryos is largely homologous to that observed in grasshopper embryos. All later-emerged sensory neurons followed the pathway established by the first pioneer neuron Ti1. Ti1 made stereotypical turns following the steering signals on epithelial and guidepost cell surfaces and eventually fasciculate with lateral motor axons from the central nervous system. When examining the peripheral nervous system development with Toll7 knockdown, a decrease in limb bud volume was observed at stage 7.7 and stage 8.0, suggesting Toll7’s potential roles in aiding cell-cell intercalation processes in Orthoptera embryos. Furthermore, a delay in Ti1 pioneer neuron development was observed with Toll7 knockdown at early developmental stages, providing evidence for Toll-Spaetzle pathway’s neurotrophic-like functions. The results of the current experiment provide the first description of the peripheral nervous system development in the cricket limb buds and further evidence of Toll-Spaetzle pathway’s neurotrophic properties.


              Miniature of Mathematically Modeling a Nonlinear, Passive Acoustic Filter
              Mathematically Modeling a Nonlinear, Passive Acoustic Filter
              This record is embargoed.
                • Embargo End Date: 2026-05-18

                Date: 2023-01-01

                Creator: Bjorn Ludwig

                Access: Embargoed



                  Playing the Fool: Analyzing the Phenomena of Iurodstvo In Contemporary Russian Cinema and Civil Society.

                  Date: 2023-01-01

                  Creator: Colby Silva Santana

                  Access: Open access

                  Of Russia's cultural and religious icons, the holy fool (iurodivy) is quite possibly the most significant one of contemporary times. The holy fool – a historical and cultural character that feigns insanity to produce moral and spiritual reflections and hide the purity of their souls – has left its traces over a significant portion of Russia's literary history, postmodern tradition, and socio-political thought. In its uniquely positioned role as a powerful form of institutional critique, today taking shape in modern-day political protest performance culture, the holy fool has often been utilized to interrogate the intertwined relationship of the Russian state and the Orthodox Church. This analysis reviews the scholarship on holy foolery and how it has manifested in various fields of study. Although scholarship on this subject is significant, there exists a lack of research into representation of the holy fool in contemporary Russian cinema. Cinema is uniquely positioned to portray holy foolery, thanks to the unique form of spectatorship the film camera allows. This thesis analyzes several case studies of 21st-century Russian cinema that feature characters representing qualities of iurodstvo and its related models. In doing so, this work traces the history and development of iurodstvo through the lens of cinema and suggests new ways of understanding holy foolery's manifestation as a political tool.


                  The Shah Bano Case: An English-Language Democratic Practice in Post-Colonial India

                  Date: 2023-01-01

                  Creator: Hafsa Hossain

                  Access: Open access

                  In 1985, Mohd. Ahmad Khan v. Shah Bano Begum, known commonly as the Shah Bano Case, became a flashpoint for Indian democracy. The Shah Bano case revolved around the maintenance of a divorced woman, not the first of its kind by any means. A case that sparked major social and political upheaval during a broader period of political turmoil, the Shah Bano case has long been interpreted as an expression of the crisis and contradictions between the democratic rights of women as citizens and the democratic rights of Muslims as a religious minority in the Indian nation-state. In the immediate aftermath of the case, critical feminist and post-colonial scholarship grappled with the dilemmas it involved, but to some extent remained caught up in those dilemmas. This thesis builds upon the important work of these and later scholars, but it also draws new attention to the specific role of the English-language public sphere in shaping the terms of debate that surrounded the case in the 1980s. This paper argues against the binary understanding of the landmark Shah Bano Case as either a failure or success of Indian secularism. I argue that the case and its aftermath demonstrate the continual nature of Indian secularism and democratic practice, especially laden in the post-Emergency era.


                  Miniature of Hemocyte-derived proteins from the lobster, <i>Homarus americanus</i>: Changes in response to an LPS immune system challenge
                  Hemocyte-derived proteins from the lobster, Homarus americanus: Changes in response to an LPS immune system challenge
                  Access to this record is restricted to members of the Bowdoin community. Log in here to view.
                  • Restriction End Date: 2029-06-01

                    Date: 2024-01-01

                    Creator: Olivia Sewon Choi

                    Access: Access restricted to the Bowdoin Community



                      Racial Bias within Capital Punishment: Instructional Comprehension

                      Date: 2024-01-01

                      Creator: Marcus Gadsden

                      Access: Open access

                      This dissertation examines the existence of racial bias within capital punishment. Since colonial times discriminatory death sentencing has impacted racial minorities, and despite living in a post-colonial epoch, the United States Justice system continues to produce alarming racial disparities. Consequently, both law reviews and social science journals indicate that race remains a significant factor in criminal trials. So, to what extent does racial bias influence capital punishment trials? Given that it does exist, how can it be alleviated? Through a statistical/qualitative analysis of psychological studies, Supreme Court cases, and jury instructions, this dissertation suggests that implicit cognitive bias continues to produce daunting realities in contemporary criminal punishment processes. Notably among juries, traditional judicial procedures have ostensibly triggered implicit bias and psychological intimidation, i.e. jury instructions. Moreover, do long and complicated jury instructions heighten instances of partial judgment? In Racial Bias within Capital Punishment: Instructional Comprehension, I argue that inaccessible jury instructions provide a space where jurors adhere to subtle racial preferences. Consequently, the swaying capacity of juries in capital punishment trials proceeds to arbitrarily produce discrepancies in sentencing rates.