Showing 4211 - 4220 of 5713 Items
Date: 1992-01-01
Creator: M. Artuso, M. Goldberg, N. Horwitz, R. Kennett, G. C., Moneti, F. Muheim, S. Playfer, Y. Rozen, P. Rubin, S. Stone, M. Thulasidas, W. M. Yao, G. Zhu, A. V. Barnes, J. Bartelt, S. E. Csorna, Z. Egyed, V. Jain, P. Sheldon, D. S. Akerib, B. Barish, M. Chadha, D. F. Cowen, G. Eigen, J. S. Miller, J. Urheim, A. J. Weinstein, D. Acosta, G. Masek, B. Ong, H. Paar
Access: Open access
- The decay 0 has been observed for the first time using the CLEO-II detector at the Cornell Electron Storage Ring. The measured branching ratio (0.170.020.02)%, agrees with the CVC (conserved vector current) prediction based on e+e-+- data. Upper limits on the branching ratios for other decays to final states including mesons are improved by an order of magnitude compared to previous measurements. © 1992 The American Physical Society.
Date: 1991-01-01
Creator: D. S. Akerib, B. Barish, D. F. Cowen, G. Eigen, R., Stroynowski, J. Urheim, A. J. Weinstein, R. Morrison, D. Schmidt, M. Procario, D. R. Johnson, K. Lingel, P. Rankin, J. G. Smith, J. Alexander, C. Bebek, K. Berkelman, D. Besson, T. E. Browder, D. G. Cassel, E. Cheu, D. M. Coffman, P. S. Drell, R. Ehrlich, R. S. Galik, M. Garcia-Sciveres, B. Geiser, B. Gittelman, S. W. Gray, D. L. Hartill, B. K. Heltsley
Access: Open access
- Using the CLEO II detector at the Cornell Electron Storage Ring, we have determined the inclusive B* cross section above the (4S) resonance in the energy range from 10.61 to 10.70 GeV. We also report a new measurement of the energy of the B*B transition photon of 46.20.30.8 MeV. © 1991 The American Physical Society.
Date: 2021-01-01
Creator: Juliet Halvorson-Taylor
Access: Open access
- This thesis is an exploration of how American presidents have used rhetoric for strategic ends in the US-China relationship. Whenever a president speaks, he is speaking to multiple audiences at the same time, yet he also must balance a number of important considerations. I used Robert Putnam’s “Two-Level Game Theory” as a framework for understanding the conditions surrounding a moment of significance in US-China relations in order to decipher a president’s rhetorical choices. The project is divided into five main parts. First, I used the UCSB American Presidency Project to identify broad trends in rhetoric towards China across presidencies. I found that every president has spoken more about China than his predecessor since the 1980s and that presidents are increasingly using negative rhetoric when talking about China. Then, I conducted three case studies, within the Putnam framework, on important points in three presidencies: Truman’s decision to withdraw aid from the KMT, Nixon’s visit to China, and Clinton’s reversal on the issue of MFN status for China. Lastly, I concluded that when “win-sets” on both sides (in these examples: on both the American and Chinese sides) are either large or small, a president should speak about China more frequently. I also looked at Trump’s presidency and the beginnings of Biden’s in order to see how these trends are playing out currently.
Date: 2012-07-01
Creator: Teerawat Wiwatpanit, Brian Powers, Patsy S. Dickinson
Access: Open access
- Although the global effects of many modulators on pattern generators are relatively consistent among preparations, modulators can induce different alterations in different preparations. We examined the mechanisms that underlie such variability in the modulatory effects of the peptide C-type allatostatin (C-AST; pQIRYHQCYFNPISCF) on the cardiac neuromuscular system of the lobster Homarus americanus. Perfusion of C-AST through the semi-intact heart consistently decreased the frequency of ongoing contractions. However, the effect of C-AST on contraction amplitude varied between preparations, decreasing in some preparations and increasing in others. To investigate this variable effect, we examined the effects of C-AST both peripherally and centrally. When contractions of the myocardium were elicited by controlled stimuli, C-AST did not alter heart contraction at the periphery (myocardium or neuromuscular junction) in any hearts. However, when applied either to the semi-intact heart or to the cardiac ganglion (CG) isolated from hearts that responded to C-AST with increased contraction force, C-AST increased both motor neuron burst duration and the number of spikes per burst by about 25%. In contrast, CG output was increased only marginally in hearts that responded to C-AST with a decrease in contraction amplitude, suggesting that the decrease in amplitude in those preparations resulted from decreased peripheral facilitation. Our data suggest that the differential effects of a single peptide on the cardiac neuromuscular system are due solely to differential effects of the peptide on the pattern generator; the extent to which the peptide induces increased burst duration is crucial in determining its overall effect on the system. © 2012. Published by The Company of Biologists Ltd.
Date: 1995-12-01
Creator: Patsy S. Dickinson
Access: Open access
- The stomatogastric nervous system of crustaceans, which controls the four parts ofthe foregut, is subject to modulation at all levels, sensory, central and motor. Modulation of the central pattern generators, which are themselves made up largely of motor neurons, providesfor increased behavioral flexibility in a variety of ways. First, each of the pattern generators can be reconfigured to give multiple outputs. Second, the "boundaries" of the different pattern generators are in fact somewhat fluid, so that the neuronal composition of the pattern generators can be altered. For example, neurons can switch from one pattern generator toanother, or two or more pattern generators can fuse to generate an entirely new pattern and thereby produce a new behavior. The mechanisms responsible for many of these modulations include alterations of both intrinsic properties and synaptic interactions between neurons. In addition, the alteration of membrane properties contributes more directly to the behavioral output by changing action potential frequency. Finally, the muscles of the stomatogastric system can themselves be modulated, with the cpvl muscle, for example, becoming an endogenous oscillator in the presence of either dopamine or the peptide FMRFamide. © 1995 by the American Society of Zoologists.
Date: 2013-05-06
Creator: Victor Zeng, Ben Ewen-Campen, Hadley W. Horch, Siegfried Roth, Taro, Mito, Cassandra G. Extavour
Access: Open access
- Most genomic resources available for insects represent the Holometabola, which are insects that undergo complete metamorphosis like beetles and flies. In contrast, the Hemimetabola (direct developing insects), representing the basal branches of the insect tree, have very few genomic resources. We have therefore created a large and publicly available transcriptome for the hemimetabolous insect Gryllus bimaculatus (cricket), a well-developed laboratory model organism whose potential for functional genetic experiments is currently limited by the absence of genomic resources. cDNA was prepared using mRNA obtained from adult ovaries containing all stages of oogenesis, and from embryo samples on each day of embryogenesis. Using 454 Titanium pyrosequencing, we sequenced over four million raw reads, and assembled them into 21,512 isotigs (predicted transcripts) and 120,805 singletons with an average coverage per base pair of 51.3. We annotated the transcriptome manually for over 400 conserved genes involved in embryonic patterning, gametogenesis, and signaling pathways. BLAST comparison of the transcriptome against the NCBI non-redundant protein database (nr) identified significant similarity to nr sequences for 55.5% of transcriptome sequences, and suggested that the transcriptome may contain 19,874 unique transcripts. For predicted transcripts without significant similarity to known sequences, we assessed their similarity to other orthopteran sequences, and determined that these transcripts contain recognizable protein domains, largely of unknown function. We created a searchable, web-based database to allow public access to all raw, assembled and annotated data. This database is to our knowledge the largest de novo assembled and annotated transcriptome resource available for any hemimetabolous insect. We therefore anticipate that these data will contribute significantly to more effective and higher-throughput deployment of molecular analysis tools in Gryllus. © 2013 Zeng et al.

Date: 2021-01-01
Creator: Anna Bosari
Access: Access restricted to the Bowdoin Community

Date: 2021-01-01
Creator: Lily Andra McVetty
Access: Access restricted to the Bowdoin Community
Date: 2016-12-01
Creator: Patsy S. Dickinson, Xuan Qu, Meredith E. Stanhope
Access: Open access
- Central pattern generators are subject to modulation by peptides, allowing for flexibility in patterned output. Current techniques used to characterize peptides include mass spectrometry and transcriptomics. In recent years, hundreds of neuropeptides have been sequenced from crustaceans; mass spectrometry has been used to identify peptides and to determine their levels and locations, setting the stage for comparative studies investigating the physiological roles of peptides. Such studies suggest that there is some evolutionary conservation of function, but also divergence of function even within a species. With current baseline data, it should be possible to begin using comparative approaches to ask fundamental questions about why peptides are encoded the way that they are and how this affects nervous system function.
Date: 2003-01-01
Creator: M. Saijo, T.W. Baumgarte, S.L. Shapiro
Access: Open access