Showing 4311 - 4320 of 5831 Items
Date: 2010-03-15
Creator: George S Isaacson, Margaret M Isaacson
Access: Open access
Biographial Note
George Steven Isaacson was born in New York on October 20, 1948, and grew up in Auburn, Maine. His father worked in a lumber business in Livermore Falls with his uncles. George was graduated from Bowdoin College and attended law school at the University of Pennsylvania, where he met his future wife, Margaret. After graduating, he clerked for Judge Thomas E. Delahanty and then went to work for a law firm in Portland, Maine. George Mitchell interviewed him for an attorney’s position with Jensen Baird law firm. At the time of this interview, he was a senior partner at Brann and Isaacson in Lewiston, Maine, an adjunct professor at Bowdoin College, and a lecturer at the University of Maine School of Law. Margaret (McGaughey) Isaacson was born in Detroit, Michigan, on May 29, 1948. She lived in New York, attended college in California and law school at the University of Pennsylvania. Margaret practiced law in Boston for four years and then accepted a clerkship with Frank Coffin in Maine. When George Mitchell was appointed U.S. attorney and permitted a third assistant U.S. attorney position, Margaret was hired. At the time of this interview, Margaret had served in the U.S. Attorney’s Office for thirty-two years.
Summary
Interview includes discussion of: George’s childhood in Auburn; growing up Jewish in Auburn; Margaret’s childhood; their meeting in law school; George’s clerkship in Maine; George’s recollections of Mitchell at Jensen Baird; Margaret’s moving to Maine for a clerkship with Frank Coffin and then as assistant U.S. attorney under Mitchell; the U.S. Attorney’s Office and Jim Brannigan; Mitchell’s management style; anecdote about Margaret’s working on drug cases with Mitchell; Mitchell’s appointment to federal judgeship; Mitchell’s 1974 gubernatorial campaign; Mitchell and rumors about the Supreme Court; Mitchell’s talent for litigation and his process in preparing a case; and Bowdoin College.
Date: 2008-11-08
Creator: Jeanne Hollingsworth
Access: Open access
Biographial Note
Jeanne Hollingsworth was born in McCook, Nebraska, on September 18, 1948, to Barbara (Davis) and John Robert Hollingsworth. She spent her early years in Holbrook, Nebraska, on her father’s cattle ranch with five siblings. The family moved to Kearney, Nebraska, when she was twelve, and from there they moved to Kitchener-Waterloo, Canada, where Jeanne attended high school and her father was in the furniture business. She attended North Georgia Military College for two years and became interested in politics because of the Vietnam War and the peace movement. She traveled for some years between Maine and Georgia, finally settling in Maine and becoming increasingly interested in organic gardening and MOFGA (Maine Organic Farmers and Gardeners Association). It was through her political activities with that group and the pesticide issue that she met Tom Bertocci. She was hired to work for Senator Mitchell in the Rockland, Maine, state field office in 1986, established good veterans’ relations, and remained until 1994. She worked in Washington, DC, for six years, first with the Occupational Safety and Health Review Commission and then at USAID. She returned to Maine in 2000 when the administration changed and has continued to be involved with local politics.
Summary
Interview includes discussion of: family and educational background; attending the North Georgia Military College; the peace movement; becoming a hippie and waitressing; the Atlanta Underground; living in Atlanta in the early ‘70s; Volkswagen bus trip to Maine; gardening and Craig; MOFGA and organic agriculture politics; working for Senator Mitchell as a case worker in the field out of the Rockland office; satisfaction with veterans’ issues and Agent Orange; getting Mitchell to visit island high schools; the veterans’ events and Mitchell’s passing out the Pearl Harbor medals; Portland and Russian sailors involved with a joint fishing venture as a trade issue; the surprise and disappointment of Mitchell leaving office; points about working as a senate aid in the field; working in Washington; and reconnecting with Mitchell employees.
Date: 2017-05-01
Creator: Sophia Walker
Access: Open access
- Contemporary American viewers are familiar with the vengeful and terrifying ghost women of recent J-Horror films such as Ringu (Nakata Hideo, 1998) and Ju-On (Shimizu Takashi, 2002). Yet in Japanese theater and literature, the threatening ghost woman has a long history, beginning with the neglected Lady Rokujo in Lady Murasaki’s 11th century novel The Tale of Genji, who possesses and kills her rivals. Throughout history, the Japanese ghost mother is hideous and pitiful, worthy of fear as well as sympathy, traits that authors and filmmakers across the centuries have exploited. This project puts together four films that have never before been discussed together -- Kinoshita Keisuke's Shinsaku Yotsuya Kaidan (1949), Nakagawa Nobuo's Tokaido Yotsuya Kaidan (1959) Mizoguchi Kenji's Ugetsu (1953), and Shindo Kaneto's Onibaba (1964) -- and discusses them as four different iterations of the demonic mother motif, presented as a projection of the Japanese collective’s postwar uncertainty over both the memory of suffering during World War II and the question of personal culpability.
Date: 2018-05-01
Creator: Shea Cristina Necheles
Access: Access restricted to the Bowdoin Community
Date: 2018-05-01
Creator: Andrew P Prescott
Access: Access restricted to the Bowdoin Community
Date: 2024-01-01
Creator: Panhasith Ung
Access: Access restricted to the Bowdoin Community
Date: 2015-01-01
Creator: Navin Sharma, Dilip Krishnappa, Sean Barker, David Irwin, Prashant, Shenoy
Access: Open access
- Reducing the energy footprint of data centers continues to receive significant attention due to both its financial and environmental impact. There are numerous methods that limit the impact of both factors, such as expanding the use of renewable energy or participating in automated demand-response programs. To take advantage of these methods, servers and applications must gracefully handle intermittent constraints in their power supply. In this paper, we propose blinking-metered transitions between a high-power active state and a low-power inactive state-as the primary abstraction for conforming to intermittent power constraints. We design Blink, an application-independent hardware-software platform for developing and evaluating blinking applications, and define multiple types of blinking policies.We then use Blink to design both a blinking version of memcached (BlinkCache) and a multimedia cache (GreenCache) to demonstrate how application characteristics affect the design of blink-aware distributed applications. Our results show that for BlinkCache, a load-proportional blinking policy combines the advantages of both activation and synchronous blinking for realistic Zipf-like popularity distributions and wind/solar power signals by achieving near optimal hit rates (within 15% of an activation policy), while also providing fairer access to the cache (within 2% of a synchronous policy) for equally popular objects. In contrast, for GreenCache, due to multimedia workload patterns, we find that a staggered load proportional blinking policy with replication of the first chunk of each video reduces the buffering time at all power levels, as compared to activation or load-proportional blinking policies.
Date: 2017-05-01
Creator: Pamela Zabala
Access: Open access
- As colleges and universities have increased efforts to make their campuses more racially and ethnically inclusive, students of color still perceive their campuses as hostile spaces to racial and ethnic minorities. On the other hand, white students often feel as though their institutions do too much, leaving administrators to balance the interests of both groups. This thesis draws on archival, ethnographic, and interview data collected at Bowdoin College to examine the relationship between students and between students and administrators given the role of students as major agents of change on college campuses. I have found that when students feel threatened by institutional change, they go into crisis and create spaces of resistance on campus. Institutions are incapable or unwilling to find solutions that meet the needs of the various constituencies within the student body. Therefore, students and administration become locked in a power struggle that produces only surface-level institutional change rather than meaningful reform in the face of rising racial tensions.
Date: 2014-05-01
Creator: Lauren A Skerritt
Access: Open access
- In the American lobster (Homarus americanus), neurogenic stimulation of the heart drives fluxes of calcium (Ca2+) into the cytoplasm of a muscle cell resulting in heart muscle contraction. The heartbeat is completed by the active transport of calcium out of the cytoplasm into extracellular and intracellular spaces. An increase in the frequency of calcium release is expected to increase amplitude and duration of muscle contraction. This makes sense because an increase in cytoplasmic calcium should increase the activation of the muscle contractile elements (actin and myosin). Since calcium cycling is a reaction-diffusion process, the extent to which calcium mediates contraction amplitude and frequency will depend on the specific diffusion relationships of calcium in this system. Despite the importance of understanding this relationship, it is difficult to obtain experimental information on the dynamics of cytoplasmic calcium. Thus, we developed a mathematical diffusion model of the myofibril (muscle cell) to simulate calcium cycling in the lobster cardiac muscle cell. The amplitude and duration of the force curves produced by the model empirically mirrored that of the experimental data over a range of calcium diffusion coefficients (1-16), nerve stimulation durations (1/6-1/3 of a contraction period), and frequencies (40-80 Hz). The characteristics that alter the response of the lobster cardiac muscle system are stimulation duration (i.e., burst duration), burst frequency, and the rate of calcium diffusion into the cell’s cytoplasm. For this reason, we developed protocols that allow parameters representing these characteristics in the calcium-force model to be determined from isolated whole muscle experiments on lobster hearts (Phillips et al., 2004). These parameters are used to predict variability in lobster heart muscle function consistent with data recorded in experiments. Within the physiological range of nerve stimulation parameters (burst duration and cycle period), calcium increased the cell’s force output for increased burst duration. For example, increased duration of stimulation increased the muscle contraction period and vice versa. In terms of diffusion, a slower rate of calcium diffusion out of the sarcoplasmic reticulum decreased both the calcium level and the contraction duration of the cell. Finally, changes in stimulation frequency did not produce changes in contraction amplitude and duration. When considered in conjunction with experimental stimulations using lobster heart muscle cells, these data illustrate the prominent role for calcium diffusion in governing contraction-relaxation cycles in lobster hearts.
Date: 2018-05-01
Creator: Sara Spicer
Access: Open access
- The well-conserved semaphorin family of guidance molecules is known to play multiple complex roles in directing the growth and orientation of dendrites and axons within the developing invertebrate central and peripheral nervous system. Additionally, the expression of select semaphorins is maintained within some highly plastic areas of the adult central nervous system, such as the mushroom bodies, where they are associated with guidance of newly-born neurons as well as with synapse formation and modification. Within the cricket species Gryllus bimaculatus, deafferentation of the prothoracic ganglia and subsequent dendritic rearrangement of the auditory interneurons is associated with fluctuations in the expression of transmembrane Sema1a and diffusible Sema2a. Here, we characterize the expression of two different variants of Gryllus Sema1a, termed Horch Sema1a and Extavour Sema1a, in tissues associated with both developmental neuronal guidance and adult structural plasticity: the embryonic limb buds, the mushroom bodies of the brain, and the non-deafferented adult prothoracic ganglion. Although we were unable to visualize the expression of Extavour Sema1a in any tissue, we demonstrate via phylogenetic analysis that both Sema1a variants have homologs in species across the Insecta class, suggesting that Extavour SEMA1a is a conserved protein sequence. We observe no expression of Horch Sema1a in the embryonic limb bud, and suspect that Extavour Sema1a, which has a high pairwise identity with Schistocerca Sema1a, could be facilitating guidance of the tibial pioneer neuron growth in the limb bud, along with Sema2a. In the adult brain, we observe a colocalization of Horch Sema1a and Sema2a in the mushroom bodies and in a vertical stripe across the calyx, which may be indicative of interactions between Horch SEMA1a and SEMA2a in maintaining synaptic plasticity and guiding newly-born Kenyon cells. We also report a colocalization of Horch Sema1a and Sema2a in the anterior and posterior of the prothoracic ganglia on the ventral side, in the region of auditory interneuron cell bodies, suggesting the possibility that auditory interneurons may express both Horch Sema1a and Sema2a, which could interact with each other or with Plexin receptors to regulate dendrite morphology at the midline.