Showing 4921 - 4930 of 5831 Items

In silico analyses suggest the cardiac ganglion of the lobster, Homarus americanus, contains a diverse array of putative innexin/innexin-like proteins, including both known and novel members of this protein family

Date: 2020-06-01

Creator: Andrew E. Christie, J. Joe Hull, Patsy S. Dickinson

Access: Open access

Gap junctions are physical channels that connect adjacent cells, permitting the flow of small molecules/ions between the cytoplasms of the coupled units. Innexin/innexin-like proteins are responsible for the formation of invertebrate gap junctions. Within the nervous system, gap junctions often function as electrical synapses, providing a means for coordinating activity among electrically coupled neurons. While some gap junctions allow the bidirectional flow of small molecules/ions between coupled cells, others permit flow in one direction only or preferentially. The complement of innexins present in a gap junction determines its specific properties. Thus, understanding innexin diversity is key for understanding the full potential of electrical coupling in a species/system. The decapod crustacean cardiac ganglion (CG), which controls cardiac muscle contractions, is a simple pattern-generating neural network with extensive electrical coupling among its circuit elements. In the lobster, Homarus americanus, prior work suggested that the adult neuronal innexin complement consists of six innexins (Homam-Inx1-4 and Homam-Inx6-7). Here, using a H. americanus CG-specific transcriptome, we explored innexin complement in this portion of the lobster nervous system. With the exception of Homam-Inx4, all of the previously described innexins appear to be expressed in the H. americanus CG. In addition, transcripts encoding seven novel putative innexins (Homam-Inx8-14) were identified, four (Homam-Inx8-11) having multiple splice variants, e.g., six for Homam-Inx8. Collectively, these data indicate that the innexin complement of the lobster nervous system in general, and the CG specifically, is likely significantly greater than previously reported, suggesting the possibility of expanded gap junction diversity and function in H. americanus.


Tau decays with one charged particle plus multiple π0's

Date: 1993-01-01

Creator: M. Procario, S. Yang, R. Balest, K. Cho, M., Daoudi, W. T. Ford, D. R. Johnson, K. Lingel, M. Lohner, P. Rankin, J. G. Smith, J. P. Alexander, C. Bebek, K. Berkelman, D. Besson, T. E. Browder, D. G. Cassel, H. A. Cho, D. M. Coffman, P. S. Drell, R. Ehrlich, R. S. Galik, M. Garcia-Sciveres, B. Geiser, B. Gittelman, S. W. Gray, D. L. Hartill, B. K. Heltsley, K. Honscheid, C. D. Jones, S. L. Jones

Access: Open access

With the CLEO-II detector at the Cornell Electron Storage Ring, we have measured branching fractions for tau lepton decay into one-prong final states with multiple π0's Bhnπ0, normalized to the branching fraction for tau decay into one charged particle and a single π0. We find Bh2π0/Bhπ0=0. 345±0.006±0.016, Bh3π0/Bhπ0=0.041 ±0.003±0. 005, and Bh4π0/Bhπ0=0.006±0.002±0.002. © 1993 The American Physical Society.


Genetic Analysis of Cellular Adhesion in Arabidopsis thaliana

Date: 2021-01-01

Creator: Andrew Close Bolender

Access: Open access

Plant cell adhesion is mediated by the extracellular matrix (ECM) or cell wall and plays an important role in plant morphogenesis and development. The amount, modification, and cleavage of pectin in the cell wall are major contributors to the adhesive properties of the ECM. To gain a more complete picture of plant cell adhesion processes, Arabidopsis thaliana seedlings were previously mutagenized and screened for hypocotyl adhesion defects. Genomic sequencing of one plant exhibiting an adhesion defect, isolate 242, showed that two mutations, one in cellulose synthase (CesA1) and another in a sugar transporter, are candidates for the causative mutation. This thesis reports that CesA1 is necessary for proper plant cell adhesion, while the sugar transporter encoded at At4g32390 is not. Dark grown seedlings homozygous for mutations in CesA1 stain in ruthenium red, indicating atypical adhesion, while those homozygous for null mutations in At4g32390 do not. Previous study of another adhesion mutant revealed ELMO1, a Golgi protein necessary for plant cell adhesion, and four additional homologs ELMO2-5 in the A. thaliana genome. Two of these homologs, ELMO2 and ELMO3, fused to GFP, colocalized with mCherry-MEM1 markers in the Golgi, but not mCherry-NLM12 ER markers, indicating that ELMO2 and ELMO3 are also Golgi proteins.


Study of D0 decays into final states with a 0 or

Date: 1991-01-01

Creator: K. Kinoshita, F. M. Pipkin, M. Procario, Richard Wilson, J., Wolinski, D. Xiao, Y. Zhu, R. Ammar, P. Baringer, D. Coppage, R. Davis, P. Haas, M. Kelly, N. Kwak, Ha Lam, S. Ro, Y. Kubota, J. K. Nelson, D. Perticone, R. Poling, S. Schrenk, G. Crawford, R. Fulton, T. Jensen, D. R. Johnson, H. Kagan, R. Kass, R. Malchow, F. Morrow, J. Whitmore, P. Wilson

Access: Open access

We have made measurements of decay modes of neutral D mesons into exclusive final states containing photons using data collected with the CLEO detector at the Cornell Electron Storage Ring. We report observation of D0'K-+-+0 (charge conjugates are implicit), and present new measurements of the branching ratios for D0'K-+0, D0'K0+0-, D0'K00, K*0, and D0'K0. Where possible, results are compared with theoretical predictions for two-body D0 decays. © 1991 The American Physical Society.


Exclusive and inclusive semileptonic decays of B mesons to D mesons

Date: 1991-01-01

Creator: R. Fulton, T. Jensen, D. R. Johnson, H. Kagan, R., Kass, F. Morrow, J. Whitmore, P. Wilson, D. Bortoletto, W. Y. Chen, J. Dominick, R. L. McIlwain, D. H. Miller, C. R. Ng, S. F. Schaffner, E. I. Shibata, I. P.J. Shipsey, W. M. Yao, M. Battle, K. Sparks, E. H. Thorndike, C. H. Wang, M. S. Alam, I. J. Kim, W. C. Li, V. Romero, C. R. Sun, P. N. Wang, M. M. Zoeller, M. Goldberg, T. Haupt

Access: Open access

We report new measurements of the branching fractions B. Combining these results with our previous measurement of BD*+l we find that the ratio of semileptonic widths for final states with a vector meson and pseudoscalar meson is (2.6-0.6-0.8+1.1+1.0) and the ratio of charged- to neutral-B-meson lifetimes is (0.89±0.19±0.13)(f00f+-) where (f00f+-) is the ratio of neutral- to charged-B-meson production at the branching fraction, we calculate |Vcb|=0.040±0.006±0.006, where the first error is statistical and the second is systematic and dominated by the uncertainty in the B-meson lifetime. © 1991 The American Physical Society.


A Foray into the Camp: Human and Ecological Liberation in Contemporary Queer Conversion Therapy Literature

Date: 2021-01-01

Creator: Mitchel Jurasek

Access: Open access

Through the analysis of two contemporary conversion therapy novels in North America, this project explores the intersections of biopolitics (specifically camp theory), queer theory, ecocriticism, and YA literature. Emily Danforth’s The Miseducation of Cameron Post and Nick White’s How to Survive a Summer are paired with scholars such as Gilles Deleuze, Felix Guattari, Joshua Whitehead, Greta Gaard, Hannah Arendt, Giorgio Agamben, Claudio Minca, Catriona Sandilands, Luce Irigaray, and Michael Marder to create a complex and intricate understanding of how ecologies impact queer youths’ experience in conversion therapy camps. The effect of such an intersectional and ecological understanding of queer becomings creates a foundation for further discovery and offers examples for current and future people to find mutual liberation with the ecologies we exist in.


Bowdoin College Catalogue (1963-1964)

Date: 1964-01-01

Access: Open access

Bowdoin College Bulletin no. 350


Solvent Effect on Excited State Proton Transfer Mechanism of 8-Amino-2-Naphthol

Date: 2021-01-01

Creator: Gabrielle Vandendries

Access: Open access

Photoacids, compounds that undergo excited state proton transfer (ESPT), have been utilized in different solar energy and lithographic applications.1, 2 The addition of functional groups and solvent can both change the ESPT mechanism of photoacids. In this study, the effect of solvent on the ESPT mechanism was explored using a model diprotic photoacid, 8-amino-2-naphthol (8N2OH). The photochemistry of 8N2OH in water and common nonaqueous solvents, acetonitrile, tetrahydrofuran (THF), and methanol, were studied using UV/Vis absorption, steady-state emission, and time-correlated single photon counting (TCPSC) emission spectroscopy. The results were analyzed using the Kamlet-Taft parameters. It was found that the ESPT mechanism of the cation in water is different from the mechanism in acetonitrile and THF. In water the excited cation forms the zwitterion, i.e. the OH site undergoes ESPT, while in acetonitrile and THF, the excited cation forms the neutral species, i.e. the NH3+ site undergoes ESPT. No ESPT was observed for 8N2OH in methanol. The effect of solvent mixtures on photoacidity was also investigated using acetonitrile and water mixtures. The solvent effects were more subtle; the time-resolved emission measurements showed the greatest stabilization of the excited neutral 8N2OH species at 20/80% acetonitrile-water mixtures. Finally, the ability to extend the solvent studies to ionic liquids, 1-ethyl-3-methylimidazolium (Im) trifluromethanesulfonate (OTF), was demonstrated. The combined studies reveal that solvent plays a large role in determining the ESPT mechanism and stabilization of 8N2OH.


Bowdoin College Catalogue (1962-1963)

Date: 1963-01-01

Access: Open access

Bowdoin College Bulletin no. 346


Unusual decay modes of D0 and D+ mesons

Date: 1991-01-01

Creator: R. Ammar, P. Baringer, D. Coppage, R. Davis, P., Haas, M. Kelly, N. Kwak, H. Lam, S. Ro, Y. Kubota, J. K. Nelson, D. Perticone, R. Poling, S. Schrenk, G. Crawford, R. Fulton, T. Jensen, D. Johnson, H. Kagan, R. Kass, R. Malchow, F. Marrow, J. Whitmore, P. Wilson, D. Bortoletto, D. N. Brown, J. Dominick, R. L. McIlwain, D. H. Miller, M. Modesitt, C. R. Ng

Access: Open access

CLEO has measured decay modes of the D0 and D+ into final states consisting of K's, s, K0's and 0's, using data taken with the CLEO detector at the Cornell Electron Storage Ring. We report new results on the decays of D0's into 4, K-K+-+, 0K+K-, 0K+-, K0K-+, 3KS0 and 0 together with some of their resonant substructure. We also present the first observation of the decay D00K+ and give limits on the doubly-Cabibbo-suppressed decays of the D0 into K+- and K+-+-. © 1991 The American Physical Society.