Showing 551 - 560 of 583 Items

Modulation of Responses to Phasic stretches by Neuromodulators GYS and SGRN in the Cardiac Central Pattern Generator of the American Lobster, H. americanus Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2016-05-01
Creator: Michael M Kang
Access: Access restricted to the Bowdoin Community
Identifying a distinct developmental module in the zebrafish dentition
Date: 2018-01-01
Creator: Caleb Matthew Gordon
Access: Open access
- In the zebrafish pharynx, the first three teeth to form, 3V1, 4V1, and 5V1, have distinct adult and embryonic morphologies, suggesting that these teeth may form using different developmental pathways. Previous studies of gene expression profiles and mutant phenotypes in 3V1, 4V1, and 5V1 have identified four genes that might be involved in dissociating these tooth modules: pitx2b, eve1, pbx1a, and pbx1b. To determine how the developmental roles of these four genes differ across 3V1, 4V1, and 5V1, and obtain a better understanding of how these three teeth develop, I performed CRISPR/Cas9– mediated knockouts in each of these genes, or analyzed embryos from a stable transgenic mutant line where available, and observed the resulting tooth germs and mineralized tooth structures via fluorescence and confocal microscopy. Preliminary results implicate pitx2 as being required for tooth mineralization, offer a possible role for pbx1a, pbx1b, and eve1 in distinguishing the developmental pathway of 3V1, and suggest that 3V1 constitutes a distinct developmental module within the early ventral dentition.

An unbiased glimpse into the sex-specific effects of ketamine treatment on rats who have experienced early life adversity. Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Lucia Marie O'Sullivan
Access: Access restricted to the Bowdoin Community

Evaluation of the Effectiveness of Probe Compounds at Predicting Anionic Pharmaceutical Sorption to Soils Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2021-01-01
Creator: Ben Cook
Access: Access restricted to the Bowdoin Community

Dispersive Shock Waves in Granular Chains This record is embargoed.
- Embargo End Date: 2026-05-18
Date: 2023-01-01
Creator: Ari Geisler
Access: Embargoed
"One Never Knew": David Foster Wallace and the Aesthetics of Consumption
Date: 2016-05-01
Creator: Jesse Ortiz
Access: Open access
- Increasingly, David Foster Wallace is becoming a cult figure among literary enthusiasts. His novels, essays, and short stories are all known for their poignant critiques of modern culture. Since his 2008 suicide, Wallace’s name has come to represent a way of thinking that rejects – and perhaps transcends – the hegemonic power of late capitalism. Wallace had a problem with pleasure. His writing often seemed to deflate or deconstruct what many people enjoy. For him, so much was “supposedly fun.” To understand Wallace’s relationship with pleasure, we must see how pleasure incorporates aesthetics and consumption. Wallace takes issue with the pleasure that comes from the aesthetics of cultural commodities. Irony produces pleasure, which turns culture into a desirable commodity. In my first chapter, I argue that Wallace’s essays challenge aesthetic pleasure by deconstructing self-reflexive irony. In his descriptions of consumer culture, Wallace evokes the feeling of disgust to undo the aesthetic pleasure of consumption. In my second chapter, I move to Infinite Jest to show how Wallace engages with irony while using it to exceed aesthetic pleasure. Infinite Jest challenges the hierarchy of aesthetics and suggests that deformity and waste can be beautiful and important. Infinite Jest demonstrates that, by trusting others instead of pursuing aesthetic ideals, people can build communities that are more honest and fulfilling than the pleasure of consumption.
Surfing the Kali Yuga: Tracking the Alt-Right on Twitter
Date: 2023-01-01
Creator: Jaida Hodge-Adams
Access: Open access
- The alt-right is a hyper-extreme, decentralized network of far-right pundits and their doggish supporters that exists almost entirely online. Consumed by conspiracy and identity, the myths of bigoted ideologies like racism, antisemitism, and transphobia are taken for granted, and their ideology calls for violent ends by violent means. In the physical world, members of the alt-right often keep their rhetoric to themselves; Online, however, they find solace in a vast, international network of websites and forums that together form one giant echo chamber into which they can dump their darkest thoughts. Though any individual member of the alt-right may operate uniquely within the context of their home country, together they form a collective, international voice whose strongest claims often transcend borders and resist state-level analysis. Unspeakable acts of violence like mass shootings, senseless killings, and acts of terrorism are unpredictable but become significantly more likely when the rhetorical atmosphere breeds hostility. By demonizing minority groups and spreading ideologies of hate, the alt-right makes these acts of violence more likely. On massive platforms like Twitter, the alt-right’s rhetoric can seep into mainstream conversations; their framing of concepts like race, gender, sexuality, and national identity are forced into relevance. Their rhetoric is euphemistic, but their message is clear, and their hate poses a real threat to people’s lives. This honors project explores the ideological and geographic features of the alt-right and their international implications, concluding that the alt-right is a globally interconnected group of actors whose conspiracies motivate lone-wolf terrorists worldwide.
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Effects of Origin Environment and Temperature Acclimation on the Temperate Coral Astrangia poculata This record is embargoed.
- Embargo End Date: 2026-05-18
Date: 2023-01-01
Creator: Deva K Holliman
Access: Embargoed

The ELMO Family of Pectin Biosynthesis Scaffold Proteins Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Margaret Elizabeth Weinstock
Access: Access restricted to the Bowdoin Community

Comparing natural variation in enhancer usage within and among Drosophila species This record is embargoed.
- Embargo End Date: 2027-05-19
Date: 2022-01-01
Creator: Justin K. Yang
Access: Embargoed