Showing 51 - 60 of 583 Items

Miniature of Eelgrass meadow structure drives epifaunal community composition more than temperature during a Marine Heat Wave in the Gulf of Maine
Eelgrass meadow structure drives epifaunal community composition more than temperature during a Marine Heat Wave in the Gulf of Maine
This record is embargoed.
    • Embargo End Date: 2029-05-16

    Date: 2024-01-01

    Creator: Nicholas Takaki Tienhui Yoong

    Access: Embargoed



      Miniature of Changes in chiropteran community structure associated with the white-nose syndrome epidemic: evidence for competitive release?
      Changes in chiropteran community structure associated with the white-nose syndrome epidemic: evidence for competitive release?
      Access to this record is restricted to members of the Bowdoin community. Log in here to view.

          Date: 2014-05-01

          Creator: Adam Eichenwald

          Access: Access restricted to the Bowdoin Community



            Miniature of The modulation of calcium-activated potassium channels for the stabilization of mammalian spinal locomotor activity
            The modulation of calcium-activated potassium channels for the stabilization of mammalian spinal locomotor activity
            This record is embargoed.
              • Embargo End Date: 2026-12-14

              Date: 2023-01-01

              Creator: Hattie Sargent Slayton

              Access: Embargoed



                Miniature of Something’s Gotta Give:  Guns, Youth, and Social Change in Denver, Colorado
                Something’s Gotta Give: Guns, Youth, and Social Change in Denver, Colorado
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                    Date: 2019-05-01

                    Creator: Carlos Manuel Holguin

                    Access: Access restricted to the Bowdoin Community



                      Miniature of I Am Bearing Myself  in the Mouth of the Sun
                      I Am Bearing Myself in the Mouth of the Sun
                      This record is embargoed.
                        • Embargo End Date: 2029-05-16

                        Date: 2024-01-01

                        Creator: Dylan Austin Richmond

                        Access: Embargoed



                          Miniature of The Things We Carried:  Effect of Exogenous Government Spending Shocks on Wartime Inflation, Evidence from the U.S. and the World
                          The Things We Carried: Effect of Exogenous Government Spending Shocks on Wartime Inflation, Evidence from the U.S. and the World
                          Access to this record is restricted to members of the Bowdoin community. Log in here to view.
                          • Restriction End Date: 2029-06-01

                            Date: 2024-01-01

                            Creator: Tingjun Huang

                            Access: Access restricted to the Bowdoin Community



                              Miniature of Efficacy of Curcumin as a Neuroprotectant Against Dibutyl Phthalate (DBP) - Induced Effects on the Mammalian Spinal Cord Locomotor Neural Network
                              Efficacy of Curcumin as a Neuroprotectant Against Dibutyl Phthalate (DBP) - Induced Effects on the Mammalian Spinal Cord Locomotor Neural Network
                              This record is embargoed.
                                • Embargo End Date: 2027-05-15

                                Date: 2024-01-01

                                Creator: Eliza Schotten

                                Access: Embargoed



                                  Miniature of Plutonic lithics record dynamics in the magmatic system beneath the Akaroa Volcanic Complex, New Zealand
                                  Plutonic lithics record dynamics in the magmatic system beneath the Akaroa Volcanic Complex, New Zealand
                                  Access to this record is restricted to members of the Bowdoin community. Log in here to view.

                                      Date: 2018-05-01

                                      Creator: Elizabeth Teeter

                                      Access: Access restricted to the Bowdoin Community



                                        Miniature of Disease on the Half-Shell: Prevalence and impact of the protistan pathogen MSX on oyster population health throughout the Gulf of Maine
                                        Disease on the Half-Shell: Prevalence and impact of the protistan pathogen MSX on oyster population health throughout the Gulf of Maine
                                        Access to this record is restricted to members of the Bowdoin community. Log in here to view.

                                            Date: 2018-05-01

                                            Creator: Madeline Schuldt

                                            Access: Access restricted to the Bowdoin Community



                                              Characterization and Quantification of AST-C Peptides in Homarus americanus Using Mass Spectrometry

                                              Date: 2015-05-01

                                              Creator: Amanda Howard

                                              Access: Open access

                                              Neuropeptides are small signaling molecules found throughout the nervous system that influence animal behavior. Using the American lobster, Homarus americanus, as a model system, this research focused on an allatostatin type-C (AST-C) peptide, pQIRYHQCYFNPISCF (disulfide bond between underlined cysteine residues), and a structurally similar crustacean peptide, SYWKQCAFNAVSCFamide. These neuropeptides influence cardiac muscle contraction patterns and stomatogastric nervous system activity in the lobster. To understand their roles, this study sought to develop a method to quantify peptides in the pericardial organ (PO) and other crustacean tissues. Overall analysis involved microdissection to isolate tissues, tissue extraction, extract purification and concentration, and analysis by chip-based nano-electrospray ionization-liquid chromatography-mass spectrometry (nanoESI-LC-MS). In the present study, pQIRYHQCYFNPISCF was identified in the PO. To quantify target peptides, internal standards were tested as recovery and calibration references. However, experiments with pQIRYHQCYFNPISCF and other peptides showed evidence of adsorptive losses during sample preparation and analysis, with improvements in recovery resulting from the use of isopropanol-prewashed polypropylene vials. Preliminary results also suggested that introducing polyethylene glycol (PEG) in solution reduced adsorptive losses for hydrophobic peptides, but may have compromised hydrophilic peptide detection. Future directions include characterizing other sources of analyte loss and developing techniques to recover these signals. Since both target peptides as detected in the lobster are post-translationally modified, other directions include identifying modified and unmodified forms of these peptides in H. americanus. Ultimately, quantifying AST-C peptides and viii identifying their modified and unmodified forms will help explain how neuropeptides regulate behavior within the lobster and more complex systems.