Showing 751 - 760 of 5701 Items

Characterization of Yellow Family Proteins in Gryllus bimaculatus

Date: 2021-01-01

Creator: Alexandra W. Rubenstein

Access: Open access

Neuronal plasticity occurs in developing nervous systems, with adult organisms rarely able to recover from neurological damage. The cricket, Gryllus bimaculatus, is useful to study neuronal plasticity due to its reorganization of the auditory system in response to injury beyond development. When a cricket ear is removed and auditory afferents severed, a rare phenomenon occurs: the dendrites of interneurons on the deafferented side cross the typically-respected midline of the prothoracic ganglion to form functional synapses with auditory afferents from the opposite side. To find proteins involved in this phenomenon, the Horch Lab assembled a de novo transcriptome from neurons in the prothoracic ganglion of G. bimaculatus. Differential gene expression analysis revealed upregulated protein yellows post-deafferentation, indicating these proteins could influence neuronal plasticity in the adult cricket CNS. I focused on characterizing the protein yellow family in the cricket. By relating protein yellows evolutionarily, mapping them onto the genome, and analyzing their sequences, I discovered the cricket has 10 yellow genes, including a newly identified yellow-r* and a block of yellows showing synteny with insect genomes. Additionally, yellow-e and -x in crickets are closely related to bacterial yellow, perhaps indicating a role for horizontal gene transfer in yellow gene evolution. The protein upregulated in the cricket CNS is closely related with yellow-f’s in other insects, indicating yellow-f is likely a secreted protein, highly expressed in the CNS, multifunctional, and conserved across insects. Characterizing yellow-f can give insight into how these upregulated proteins might be related to neuronal plasticity in G. bimaculatus.


Miniature of Palimpsestuous London: Spatial and Temporal Layering in Fin-de-Siècle Victorian Fiction
Palimpsestuous London: Spatial and Temporal Layering in Fin-de-Siècle Victorian Fiction
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      Date: 2015-05-01

      Creator: Elisabeth A Strayer

      Access: Access restricted to the Bowdoin Community



        Miniature of From Homer to the Roman Empire: The Reception of Music in Antiquity
        From Homer to the Roman Empire: The Reception of Music in Antiquity
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            Date: 2023-01-01

            Creator: Augustine Segger

            Access: Access restricted to the Bowdoin Community



              Miniature of Timing the Paleozoic Oxygenation of the Deep Ocean Using Thallium Isotopes
              Timing the Paleozoic Oxygenation of the Deep Ocean Using Thallium Isotopes
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                • Embargo End Date: 2028-05-17

                Date: 2023-01-01

                Creator: Jean Nikolas R. Clemente

                Access: Embargoed



                  Bowdoin College Academic Handbook (2018-2019)

                  Date: 2018-01-01

                  Access: Open access



                  Miniature of Sex- and age-specific susceptibility of parvalbumin neurons to DNA methylation in a model of early life adversity
                  Sex- and age-specific susceptibility of parvalbumin neurons to DNA methylation in a model of early life adversity
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                    • Embargo End Date: 2025-05-19

                    Date: 2022-01-01

                    Creator: Alissa Chen

                    Access: Embargoed



                      Miniature of Antimicrobial Compounds in the Lobster, <i>Homarus americanus</i>: An Investigation of Lobster Shell Extracts
                      Antimicrobial Compounds in the Lobster, Homarus americanus: An Investigation of Lobster Shell Extracts
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                        • Embargo End Date: 2027-05-19

                        Date: 2022-01-01

                        Creator: Usira Ahmed Ali

                        Access: Embargoed



                          Bowdoin College Course Guide (Fall 2018)

                          Date: 2018-01-01

                          Access: Open access



                          Miniature of Illumination, Inspiration, and Inquisition: The 15th and 16th century reception and reaction of Dante’s <i>Divina Commedia</i> in Spain
                          Illumination, Inspiration, and Inquisition: The 15th and 16th century reception and reaction of Dante’s Divina Commedia in Spain
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                            • Embargo End Date: 2025-05-19

                            Date: 2022-01-01

                            Creator: Francesca Mauro

                            Access: Embargoed



                              Bowdoin College Catalogue (1847 Spring)

                              Date: 1847-01-01

                              Access: Open access