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Miniature of Metabolic Glycan Labeling in Bacteria Using Rare Azido L-sugars
Metabolic Glycan Labeling in Bacteria Using Rare Azido L-sugars
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  • Restriction End Date: 2027-06-01

    Date: 2022-01-01

    Creator: Phuong Luong

    Access: Access restricted to the Bowdoin Community

      Miniature of The Role of Protein Kinases ROG1 and SRF6 in the WAK Stress Response Pathway
      The Role of Protein Kinases ROG1 and SRF6 in the WAK Stress Response Pathway

      Date: 2015-05-01

      Creator: Jaepil E Yoon

      Access: Open access

      Miniature of Identification of Mutations in WAK Locus in Arabidopsis thaliana
      Identification of Mutations in WAK Locus in Arabidopsis thaliana
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          Date: 2017-05-01

          Creator: Arman Ashrafi

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            Miniature of Evaluation of design parameters for monosaccharide probes used in the metabolic labeling of bacterial glycans
            Evaluation of design parameters for monosaccharide probes used in the metabolic labeling of bacterial glycans
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                Date: 2024-01-01

                Creator: Sophia Elisabeth Nigrovic

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                  Miniature of Photochemistry of Cyano-Substituted 8-Amino-2-Naphthol
                  Photochemistry of Cyano-Substituted 8-Amino-2-Naphthol
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                    • Embargo End Date: 2026-05-20

                    Date: 2021-01-01

                    Creator: Jialin Xie

                    Access: Embargoed

                      Miniature of Identification of MPKs Involved in the Wall Associated Kinase Regulated Stress Response in Arabidopsis thaliana
                      Identification of MPKs Involved in the Wall Associated Kinase Regulated Stress Response in Arabidopsis thaliana
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                          Date: 2013-05-01

                          Creator: Patrick J Lariviere

                          Access: Access restricted to the Bowdoin Community

                            Miniature of Thioglycosides modulate bacterial glycosylation
                            Thioglycosides modulate bacterial glycosylation
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                                Date: 2023-01-01

                                Creator: Isabella de la Luz Quintana

                                Access: Access restricted to the Bowdoin Community

                                  Miniature of Hemocyte-derived proteins from the lobster, <i>Homarus americanus</i>: Changes in response to an LPS immune system challenge
                                  Hemocyte-derived proteins from the lobster, Homarus americanus: Changes in response to an LPS immune system challenge
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                                  • Restriction End Date: 2029-06-01

                                    Date: 2024-01-01

                                    Creator: Olivia Sewon Choi

                                    Access: Access restricted to the Bowdoin Community

                                      Miniature of Investigating the Role of <i>Helicobacter pylori</i> Glycan Biosynthesis in Modulating Host Immune Cell Recognition
                                      Investigating the Role of Helicobacter pylori Glycan Biosynthesis in Modulating Host Immune Cell Recognition
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                                          Date: 2023-01-01

                                          Creator: Katharine Barrett

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                                            Miniature of Characterization of the ELMO2 Protein that Mediates Cell Adhesion in <i>Arabidopsis thaliana</i>
                                            Characterization of the ELMO2 Protein that Mediates Cell Adhesion in Arabidopsis thaliana

                                            Date: 2022-01-01

                                            Creator: Devaki Rajiv

                                            Access: Open access

                                            The binding of adjacent cells to one another, or cell adhesion, is critical for the growth and development of multicellular organisms. In plant cells, much evidence suggests that the amount and modification of pectin in the cell wall largely determines how well cell adhesion occurs. ELMO1 is a Golgi protein involved in pectin-mediated cellular adhesion, and mutations in ELMO1 lead to disrupted cell organization in Arabidopsis. ELMO1 is predicted to be a scaffold for pectin biosynthesis enzymes, and thus its absence leads to the adhesion-defective phenotype of elmo1-/- plants. There are four other ELMO homologues (ELMO2,3,4 and 5) which remain to be characterized as to their function and role in cell adhesion. This thesis focuses on the characterization of ELMO2, which has 79% amino acid similarity with ELMO1. A genetic analysis that evaluated elmo2 double mutants revealed that ELMO2 and ELMO1 have redundant functions. elmo1-/-/2-/- double mutants, but not elmo2-/- or elmo1-/- single mutants, have reduced tensile strengths. While elmo1-/- phenotypes are most pronounced in liquid media, they are partially rescued by growth on agar, suggesting a role of turgor in maintaining cell adhesion. Like ELMO1, ELMO2-GFP colocalizes with Golgi markers. The results suggest that like ELMO1, ELMO2 also functions as a scaffold for pectin biosynthesis enzymes in the Golgi.

                                            Biochemistry Molecular Biology Biology Genetics Plant Biology Arabidopsis Cell Biology Helicobacter pylori Life Sciences Molecular Genetics Carbohydrates Drosophila Genetics and Genomics WAK Candida albicans Development H. pylori Immunology and Infectious Disease Medicine and Health Sciences Molecular and Cellular Neuroscience Organic Chemistry antibiotic resistance eyes absent lipopolysaccharide pectin AMPs Adhesion Analytical Chemistry Animals Bacteria Bacterial Infections and Mycoses Bioinformatics Cell Wall Developmental Biology Evolution Homarus americanus Inorganic Chemistry LPS Laboratory and Basic Science Research Microbiology PRE Peptoids Plant Breeding and Genetics Plant Pathology ROG1 Saccharomyces cerevisiae Signaling WAKs adhesion bacteria bioorthogonal chemistry chemical biology enhancers glycan glycoprotein glycosylation metabolic oligosaccharide engineering 2-picolinic acid 2-picolylamine 5-mC AGO ATAC-Seq ATAC-seq Active Force Activity testing Afterload Animal Experimentation and Research Animal Structures Auditory Azide B fragilis B. fragilis Bacterial monosaccharides Bacteriology Bacteroides fragilis Behavioral Neurobiology Bioactivity directed approach Biological fitness Bioorthogonal Chemistry C. jejuni CRISPR Candidiasis Cardiac Output Catalysis Cell Elongation & Growth Cell and Developmental Biology Cellular and Molecular Physiology Chemistry Chlorophyll fluorescence Chromatin Click chemistry Comparative and Evolutionary Physiology Compensatory Computational Chemistry DFT DNA methylation DNA repair Danio rerio Diseases Drosophila melanogaster ELMO5 ESPT Early Life Adversity Enhancers Environmental Chemistry Eya Eyes Absent Fgf Fluorescence Gene expression Gene regulation Genetic analysis Genome Glycans Glycoproteins Glycosylation Gryllus H pylori Heart Heartbeat Hydrogen Activation Immune System Diseases Immunology of Infectious Disease Immunotherapy Kirby-Bauer Lobster Lobster shell cuticles MOF MPK Marine Biology Metabolic Labeling Metabolic Oligosaccharide Engineering Metabolic oligosaccharide engineering N-Heterocylic Carbenes N-substituted glycines NBD Neuronal plasticity OG OGs Odontogenesis PARP PRC1 PRC2 PT Parvalbumin Pathogenicity PcG Peptide Phosphoproteomics Photoacid Physical Chemistry Physiology Pilin Plant Defense Plant Sciences Plasticity Plesiomonas shigelloides Polycomb Polycomb Response Elements Preload Probes Pseudaminic acid Pseudopotentials QMC REM2 RNA-binding protein RNA-seq analysis Ralstonia pickettii Receptors SGRN SRF6 Sciara coprophila Semaphorins Sex-Differences She3 Signal Transduction Pathway Small molecule inhibitor Small molecule inhibitors Solar-induced fluorescence Spaetzle Staphylococcus aureus Stereoselective Trifluoromethylation Stress Response Stress response Structural Biology Sugar Systems and Integrative Physiology Temperature Thioglycosides Toll Transcription Turfgrass Uptake Vibrio vulnificus Virulence WAK1 Wall Associated Kinases (WAKs) Wnt Yeast alternative splicing aminonaphthol antibiotics arabidopsis arabidopsis thaliana asymmetric mRNA transport The disciplines are: atenolol auditory system auto-regulation axon pathfinding azide azidosugars bacterial glycans bio-oil aging biochemistry bioinformatics catalyst cell adhesion cell adhesion; cell wall; ELMO; redundancy; compensation; scaffold cell expansion cell wall cellulose cesa1 chemistry chlorophyll chromatin cis-regulatory coinage metal coniferyl alcohol cricket crispr cyanonaphthol dendritic cells drosophila drought drug discovery dsRNA knockdowns elmo enantioselectivity enhancer epigenetics esterase evolution extracellular matrix (ECM) eya eye development fitness fluorescent probes gastric adenocarcinoma cells gene regulation genetic regulation glycan biosynthesis glycans glycobiology glycomics glycosylation mutant golgi grp heterocyclic hydrogen activation hyphal growth ibuprofen immune response immunology inhibitors kinase lamella ligand lignin lik1 lobster mRNA mRNA transport metabolic glycan labeling metabolic inhibitors metabolic labeling metabolic labelling microbiology middle lamella midline crossing naphthol neuropeptide pathogenesis peracetylated azido sugars phase variation phenotypic diversity phosphorylation photocatalysis photocatalyst photoreceptor axon targeting photosynthesis phylogenetic analysis plant intercellular adhesion pleiotropy post-transcriptional regulation prefrontal cortex promoter protein complex protein glycosylation proteomics protonated quinone methide pseudohyphae pseudohyphal growth pyrolysis oils radiation retinal determination network ruthenium red scaffold siRNA signaling small molecule inhibitor synthetic fuels translational research transport transvection trifluoromethylation wak wall-associated kinase