Showing 1 - 10 of 44 Items

Attention training toward and away from threat in social phobia: Effects on subjective, behavioral, and physiological measures of anxiety

Date: 2012-01-01

Creator: Alexandre Heeren, Hannah E. Reese, Richard J. McNally, Pierre Philippot

Access: Open access

Social phobics exhibit an attentional bias for threat in probe detection and probe discrimination paradigms. Attention training programs, in which probes always replace nonthreatening cues, reduce attentional bias for threat and self-reported social anxiety. However, researchers have seldom included behavioral measures of anxiety reduction, and have never taken physiological measures of anxiety reduction. In the present study, we trained individuals with generalized social phobia (n = 57) to attend to threat cues (attend to threat), to attend to positive cues (attend to positive), or to alternately attend to both (control condition). We assessed not only self-reported social anxiety, but also behavioral and physiological measures of social anxiety. Participants trained to attend to nonthreatening cues demonstrated significantly greater reductions in self-reported, behavioral, and physiological measures of anxiety than did participants from the attend to threat and control conditions. © 2011 Elsevier Ltd.


The premonitory urge to tic: Measurement, characteristics, and correlates in older adolescents and adults

Date: 2014-01-01

Creator: Hannah E. Reese, Lawrence Scahill, Alan L. Peterson, Katherine Crowe, Douglas W., Woods, John Piacentini, John T. Walkup, Sabine Wilhelm

Access: Open access

In addition to motor and/or vocal tics, many individuals with Tourette syndrome (TS) or chronic tic disorder (CTD) report frequent, uncomfortable sensory phenomena that immediately precede the tics. To date, examination of these premonitory sensations or urges has been limited by inconsistent assessment tools. In this paper, we examine the psychometric properties of a nine-item self-report measure, the Premonitory Urge to Tic Scale (PUTS) and examine the characteristics and correlates of the premonitory urge to tic in a clinical sample of 122 older adolescents and adults with TS or CTD. The PUTS demonstrated adequate internal consistency, temporal stability, and concurrent validity. Premonitory urges were endorsed by the majority of individuals. Most individuals reported some relief from the urges after completing a tic and being able to stop their tics even if only temporarily. Degree of premonitory urges was not significantly correlated with age, and we did not observe any gender differences. Degree of premonitory urges was significantly correlated with estimated IQ and tic severity, but not severity of comorbid obsessive-compulsive disorder or attention-deficit hyperactivity disorder. Also, it was not related to concomitant medication status. These findings represent another step forward in our understanding of the premonitory sensations associated with TS and CTD. © 2013.


Homotypic and heterotypic continuity of fine-grained temperament during infancy, toddlerhood, and early childhood

Date: 2008-07-01

Creator: Samuel P. Putnam, Mary K. Rothbart, Maria A. Gartstein

Access: Open access

Longitudinal continuity was investigated for fine-grained and factor-level aspects of temperament measured with the Infant Behaviour Questionnaire-Revised (IBQ-R), Early Childhood Behaviour Questionnaire (ECBQ), and Children's Behaviour Questionnaire (CBQ). Considerable homotypic continuity was found. Convergent and discriminant validity of the measures was supported, as all fine-grained dimensions exhibited stability across adjacent measurement periods, and all scales found on both the ECBQ and CBQ were most highly correlated with their equivalent scales. At the factor level, Surgency and Negative Affect factors were stable across all time points, and Effortful Control/Regulatory Capacity was stable across adjacent time periods. High-Intensity Pleasure, Activity Level, and Impulsivity contributed strongly to continuity of Surgency, and Sadness, Frustration, and Falling Reactivity played strong roles in the continuity of Negative Affect. Heterotypic continuity was also found. High levels of Infant Surgency predicted high toddler Effortful Control, whereas high toddler Surgency predicted low Effortful Control in preschoolers. Infant Surgency dimensions especially predicted Toddler Attention Shifting and Low-Intensity Pleasure, and toddler Activity Level was most closely associated with later deficits in Effortful Control. Inverse relations were also obtained between Negative Affect and Effortful Control, with substantial negative connections between toddler Negative Affect and preschool Attention Focusing and Inhibitory Control. Copyright © 2008 John Wiley & Sons, Ltd.


Theta oscillations support active exploration in human spatial navigation

Date: 2022-11-15

Creator: Elizabeth R. Chrastil, Caroline Rice, Mathias Goncalves, Kylie N. Moore, Syanah C. Wynn, Chantal E. Stern, Erika Nyhus

Access: Open access

Active navigation seems to yield better spatial knowledge than passive navigation, but it is unclear how active decision-making influences learning and memory. Here, we examined the contributions of theta oscillations to memory-related exploration while testing theories about how they contribute to active learning. Using electroencephalography (EEG), we tested individuals on a maze-learning task in which they made discrete decisions about where to explore at each choice point in the maze. Half the participants were free to make active decisions at each choice point, and the other half passively explored by selecting a marked choice (matched to active exploration) at each intersection. Critically, all decisions were made when stationary, decoupling the active decision-making process from movement and speed factors, which is another prominent potential role for theta oscillations. Participants were then tested on their knowledge of the maze by traveling from object A to object B within the maze. Results show an advantage for active decision-making during learning and indicate that the active group had greater theta power during choice points in exploration, particularly in midfrontal channels. These findings demonstrate that active exploration is associated with theta oscillations during human spatial navigation, and that these oscillations are not exclusively related to movement or speed. Results demonstrating increased theta oscillations in prefrontal regions suggest communication with the hippocampus and integration of new information into memory. We also found evidence for alpha oscillations during active navigation, suggesting a role for attention as well. This study finds support for a general mnemonic role for theta oscillations during navigational learning. © 2022


Assessing longitudinal pathways between maternal depressive symptoms, parenting self-esteem and infant temperament

Date: 2019-08-01

Creator: Lea Takács, Filip Smolík, Samuel Putnam

Access: Open access

Background Previous studies of relations between parenting self-concepts, parental adjustment and child temperament have been ambiguous regarding the direction of influence; and have rarely followed families from pregnancy through the first year of life. The current study examines change and stability in maternal depressive symptoms, parenting competences and child temperament through the perinatal period until nine months postpartum. Methods Czech mothers (N = 282) participated at three time points: the third trimester of pregnancy (Time 1), six weeks (Time 2) and nine months postpartum (Time 3). Questionnaire data concerned depressive symptoms (T1, T2, T3), maternal parenting self-esteem (T1, T2) and sense of competence (T3), and child temperament (T2, T3). A path model was used to examine concurrent and longitudinal relations between these variables. Results The analyses indicated longitudinal stability of all constructs, as well as concurrent relations between them. Longitudinal relations supported child-to-parent, rather than parent-to-child, effects: child difficult temperament predicted decreases in perceived maternal parenting competences, but maternal variables did not predict change in infant temperament. In addition, we observed weak mutual relations between maternal depression levels and parenting competences, such that maternal depression diminished perceived parenting competences that in turn contributed to higher levels of depression. Conclusion Mothers’ confidence in their ability to parent is influenced by their experience with a difficult infant and by their depressive symptoms during the child’s first year of life. Depressive symptoms are, in turn, aggravated by mothers’ low perceived competences in the parenting role.


Reactivity and regulation: The impact of Mary Rothbart on the study of temperament

Date: 2008-07-01

Creator: Samuel P. Putnam, Cynthia A. Stifter

Access: Open access

Through her theoretical and empirical work, Mary Rothbart has had a profound impact on the scientific understanding of infant and child temperament. This special issue honors her contributions through the presentations of original, contemporary studies relevant to three primary themes in Rothbart's conceptual approach: the expansive scope and empirically-derived structure of temperament, the importance of considering developmental change, and the interplay of reactive and regulatory processes. In addition to summarizing these themes, this introductory article acknowledges the ways Mary has spurred progress in the field through methodological advances, institutional service, and pedagogy. Copyright © 2008 John Wiley & Sons, Ltd.


Prediction of "fear" acquisition in healthy control participants in a de novo fear-conditioning paradigm

Date: 2007-01-01

Creator: Michael W. Otto, Teresa M. Leyro, Kelly Christian, Christen M. Deveney, Hannah, Reese, Mark H. Pollack, Scott P. Orr

Access: Open access

Studies using fear-conditioning paradigms have found that anxiety patients are more conditionable than individuals without these disorders, but these effects have been demonstrated inconsistently. It is unclear whether these findings have etiological significance or whether enhanced conditionability is linked only to certain anxiety characteristics. To further examine these issues, the authors assessed the predictive significance of relevant subsyndromal characteristics in 72 healthy adults, including measures of worry, avoidance, anxious mood, depressed mood, and fears of anxiety symptoms (anxiety sensitivity), as well as the dimensions of Neuroticism and Extraversion. Of these variables, the authors found that the combination of higher levels of subsyndromal worry and lower levels of behavioral avoidance predicted heightened conditionability, raising questions about the etiological significance of these variables in the acquisition or maintenance of anxiety disorders. In contrast, the authors found that anxiety sensitivity was more linked to individual differences in orienting response than differences in conditioning per se. © 2007 Sage Publications.


The Wisconsin Card Sorting Test and the cognitive assessment of prefrontal executive functions: A critical update

Date: 2009-12-01

Creator: Erika Nyhus, Francisco Barceló

Access: Open access

For over four decades the Wisconsin Card Sorting Test (WCST) has been one of the most distinctive tests of prefrontal function. Clinical research and recent brain imaging have brought into question the validity and specificity of this test as a marker of frontal dysfunction. Clinical studies with neurological patients have confirmed that, in its traditional form, the WCST fails to discriminate between frontal and non-frontal lesions. In addition, functional brain imaging studies show rapid and widespread activation across frontal and non-frontal brain regions during WCST performance. These studies suggest that the concept of an anatomically pure test of prefrontal function is not only empirically unattainable, but also theoretically inaccurate. The aim of the present review is to examine the causes of these criticisms and to resolve them by incorporating new methodological and conceptual advances in order to improve the construct validity of WCST scores and their relationship to prefrontal executive functions. We conclude that these objectives can be achieved by drawing on theory-guided experimental design, and on precise spatial and temporal sampling of brain activity, and then exemplify this using an integrative model of prefrontal function [i.e., Miller, E. K. (2000). The prefrontal cortex and cognitive control. Nature Reviews Neuroscience, 1, 59-65.] combined with the formal information theoretical approach to cognitive control [Koechlin, E., & Summerfield, C. (2007). An information theoretical approach to prefrontal executive function. Trends in Cognitive Sciences, 11, 229-235.]. © 2009 Elsevier Inc.


Feasibility and acceptability of an online mindfulness-based group intervention for adults with tic disorders

Date: 2021-12-01

Creator: Hannah E. Reese, W. Alan Brown, Berta J. Summers, Jin Shin, Grace, Wheeler, Sabine Wilhelm

Access: Open access

Abstract: Background: Preliminary research suggests that a mindfulness-based treatment approach may be beneficial for adults with tic disorders. In the present study, we report on the feasibility, acceptability, safety, and symptomatic effect of a novel online mindfulness-based group intervention for adults with Tourette syndrome or persistent tic disorder. Data from this study will directly inform the conduct of a funded randomized controlled trial comparing the efficacy of this intervention to another active psychological intervention. Methods: One cohort of adults with Tourette syndrome participated in an 8-week online mindfulness-based group intervention. Measures of feasibility, acceptability, and safety were administered throughout and at posttreatment. Self-reported measures of mindfulness and clinician-rated measures of tic severity and impairment were administered at baseline and posttreatment. Results: Data on refusal, dropout rate, attendance, participant satisfaction, and safety suggest that this is a feasible and acceptable intervention. However, participant adherence to home practice was lower than anticipated. Mindfulness, tic severity, and tic-related impairment only modestly improved from baseline to posttreatment. Qualitative analysis of participant feedback revealed aspects of the intervention that were most helpful and also areas for improvement. Conclusions: Data suggest that although this is a feasible and acceptable intervention, it should be modified to enhance participant adherence, more successfully engage the target mechanism, and optimize outcomes. Trial registration: Clinicaltrials.gov registration #NCT03525626. Registered on 24 April 2018


Neurocognitive predictors of treatment response to randomized treatment in adults with tic disorders

Date: 2017-03-06

Creator: Amitai Abramovitch, Lauren S. Hallion, Hannah E. Reese, Douglas W. Woods, Alan, Peterson, John T. Walkup, John Piacentini, Lawrence Scahill, Thilo Deckersbach, Sabine Wilhelm

Access: Open access

Tourette's disorder (TS) and chronic tic disorder (CTD) are neurodevelopmental disorders characterized by involuntary vocal and motor tics. Consequently, TS/CTD have been conceptualized as disorders of cognitive and motor inhibitory control. However, most neurocognitive studies have found comparable or superior inhibitory capacity among individuals with TS/CTD relative to healthy controls. These findings have led to the hypothesis that individuals with TS/CTD develop increased inhibitory control due to the constant need to inhibit tics. However, the role of cognitive control in TS/CTD is not yet understood, particularly in adults. To examine the role of inhibitory control in TS/CTD, the present study investigated this association by assessing the relationship between inhibitory control and treatment response in a large sample of adults with TS/CTD. As part of a large randomized trial comparing behavior therapy versus supportive psychotherapy for TS/CTD, a battery of tests, including tests of inhibitory control was administered to 122 adults with TS/CTD at baseline. We assessed the association between neuropsychological test performance and change in symptom severity, as well as compared the performance of treatment responders and non-responders as defined by the Clinical Global Impression Scale. Results indicated that change in symptoms, and treatment response were not associated with neuropsychological performance on tests of inhibitory control, intellectual ability, or motor function, regardless of type of treatment. The finding that significant change in symptom severity of TS/CTD patients is not associated with impairment or change in inhibitory control regardless of treatment type suggests that inhibitory control may not be a clinically relevant facet of these disorders in adults.