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Miniature of The Regulatory Effect of High Dopamine on the Hyperpolarization-Activated Inward Current  (I<sub>h</sub>) and its Role in the Stability and Rhythmicity of Mammalian Locomotor Neural Networks
The Regulatory Effect of High Dopamine on the Hyperpolarization-Activated Inward Current (Ih) and its Role in the Stability and Rhythmicity of Mammalian Locomotor Neural Networks
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  • Restriction End Date: 2025-06-01

    Date: 2022-01-01

    Creator: Abigail Raymond

    Access: Access restricted to the Bowdoin Community



      Fall forward, spring back: Drivers of synchrony in the sea star crawl-bounce gait transition

      Date: 2024-01-01

      Creator: Brady R Nichols

      Access: Open access

      The Froude number is the ratio of kinetic energy to gravitational potential energy used during locomotion and is often used to analyze gait transitions. Here, I compare and contrast the human walk-run gait transition, which occurs at a consistent Froude number of 1 because there exists a mechanical speed limit to walking, and the sea star crawl-bounce gait transition, which occurs around Froude numbers of 1*10^-3. In this thesis I investigate why sea stars exhibit two gaits despite lacking brains and moving at Froude numbers far below other known gait transitions, hypothesizing (1) that the crawl-bounce transition may be mechanical and thus still depends on the Froude number, and (2) that the crawl-bounce transition is best modeled gradually compared to the instantaneous human walk-run transition. Thirty sea stars were filmed and the resulting kinematic data is used here to inform thinking about the crawl-bounce transition. I first discuss damped driven harmonic motion of a single oscillator, but eventually turn to using coupled oscillators and deriving that a coupling constant between metronomes on a moving base is the Froude number, which is therefore relevant for the crawl-bounce transition. I lastly discuss a purely mathematical analogue of the crawl-bounce transition as a Hopf bifurcation in horizontal speed and vertical velocity phase space, which leads to a rough model with results qualitatively similar to observed kinematic data from films, and indicates that a gradual transition is in fact a good fit for the crawl-bounce transition.


      Miniature of The impact of temperature on the sea star oscillatory gait
      The impact of temperature on the sea star oscillatory gait
      This record is embargoed.
        • Embargo End Date: 2025-05-14

        Date: 2020-01-01

        Creator: Emma Victoria Bertke

        Access: Embargoed



          Miniature of The modulation of calcium-activated potassium channels for the stabilization of mammalian spinal locomotor activity
          The modulation of calcium-activated potassium channels for the stabilization of mammalian spinal locomotor activity
          This record is embargoed.
            • Embargo End Date: 2026-12-14

            Date: 2023-01-01

            Creator: Hattie Sargent Slayton

            Access: Embargoed